醋酸甲地孕酮所致肌阵挛1例

IF 2.9 4区医学 Q2 CLINICAL NEUROLOGY

Journal of Geriatric Psychiatry and Neurology Pub Date : 2023-09-22 DOI:10.53991/jgn.2023.00038

Su Min Park, Jung-Ju Lee

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引用次数: 0

摘要

肌阵挛是一种临床症状，其特征是肌肉或一组肌肉短暂、不自主、突然收缩或停止收缩，可与脑部疾病、癫痫性疾病和药物有关。醋酸甲地孕酮(Megestrol acetate, MGA)是黄体酮的合成衍生物，已广泛应用于临床，用于恶性肿瘤合并严重厌食症患者的食欲增加。我们经历了一位68岁的女性患者，她在服用MGA后出现了肌阵挛，在此报告这个病例。我们的病例表明MGA可能是可逆性肌阵挛的一个原因。隐源性肌阵挛可在伴有恶性肿瘤的消瘦综合征患者中出现。这可能是此类患者发生不明原因的肌阵挛的原因。关键词:肌阵挛;孕酮;消耗综合征

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Myoclonus associated with megestrol acetate: a case report

Myoclonus is a clinical sign characterized by brief, involuntary, jerky contraction or lapse of contraction of a muscle or a group of muscles, which can be associated with cerebral disorders, epileptic disorders, and drugs. Megestrol acetate (MGA) is a synthetic derivative of progestin, which has been widely used in clinical practice for increasing appetite in patients with severe anorexia associated with malignancies. We experienced a 68-year-old female patient who experienced myoclonus after administration of MGA and herein report the case. Our case indicated that MGA may be a cause of reversible myoclonus. Cryptogenic myoclonus can be encountered in patients with wasting syndromes associated with malignancies. It may be a cause of unexplained myoclonus in such patients. Keywords: Myoclonus; Progestins; Wasting syndrome

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来源期刊

Journal of Geriatric Psychiatry and Neurology 医学-精神病学

CiteScore

6.20

自引率

0.00%

发文量

审稿时长

>12 weeks

期刊介绍： Journal of Geriatric Psychiatry and Neurology (JGP) brings together original research, clinical reviews, and timely case reports on neuropsychiatric care of aging patients, including age-related biologic, neurologic, and psychiatric illnesses; psychosocial problems; forensic issues; and family care. The journal offers the latest peer-reviewed information on cognitive, mood, anxiety, addictive, and sleep disorders in older patients, as well as tested diagnostic tools and therapies.