睾丸内胚层窦肿瘤肝脏和肠道结构的免疫组化研究。

Basic and applied histochemistry Pub Date : 1988-01-01
M Martinazzi, F Crivelli, C Zampatti
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引用次数: 0

摘要

在6例内胚层窦肿瘤(EST)和睾丸胚胎癌的连续切片中,有2例发现肝脏和肠组织的特征,显示了内胚层窦区。肝巢表现为小管、索和巨大的多核细胞,pas阳性,甲胎蛋白(AFP)和细胞角蛋白(CK)免疫反应。肠小管被发现在EST区域,其特点是缺乏细胞异型性。细胞质中弥漫着PAS-、AFP-和ck -反应,并伴有刷状边缘或CEA的顶端染色,这是非常明显的。EST显示胚胎内和胚胎外内胚层发育的潜力,可能被解释为单系畸胎瘤。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Immunohistochemical study of hepatic and enteric structures in testicular endodermal sinus tumors.

Features of hepatic and enteric tissue have been detected in serial sections of 2 out of 6 endodermal sinus tumors (EST) and embryonal carcinomas of the testis showing endodermal sinus areas. Hepatic nests, which appeared as tubules, cords and giant multinucleated cells, were PAS-positive as well as immunoreactive for alphafetoprotein (AFP) and cytokeratin (CK). Enteric tubules were found within EST areas and were characterized by their lack of cell atypism. The presence of diffuse PAS-, AFP- and CK-reactivity in cytoplasm, together with a brush border or an apical staining for CEA, were quite distinctive. EST showed a potential for both intra- and extraembryonal endodermic development and may be interpreted as a monophyletic teratoma.

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