SPECIAL FEATURES OF INFLAMMATORY RESPIRATION WAYS DISEASES WITH THE INFLUENCE OF HYPOTHYROID STATUS AND ITS CORRECTION (REVIEW)

The purpose of the work – to analyze the literature data concerning the effect of reducingthe content of the thyroid gland (TG), as well as its correction with hormone replacementtherapy on the course of chronic obstructive pulmonary disease (COPD) and bronchialasthma (BA).Conclusions. On the basis of literature data, pathophysiological evidence of theinterrelationship of changes in thyroid status and chronic inflammatory process inthe respiratory tract (RT), as well as the effect of hormone replacement therapy forhypothyroidism on the course of these comorbid conditions, were established. Theanalyzed literary sources present the data of new studies: epidemiological, experimentaland clinical with the involvement of modern laboratory (immunological and molecularbiological in particular) and instrumental methods, which form a new point of view on therelationship between inflammation in the thyroid gland and hypothyroid status, and alsohighlight aspects of the influence of hormone replacement therapy on the development ofthe pathological process in RT with COPD and BA.