日常生活功能活动测量方法的验证:加州大学圣地亚哥分校绩效技能评估的韩文版本

Chaelin Joo, Kayoung Kim, Won Hye Lee, Joo Hyun Han, Eunjung Noh, Seon Jin Yim
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摘要

目的:本研究的目的是评估加州大学圣地亚哥分校基于绩效的技能评估,中间措施验证(K-UPSA-2-VIM)在痴呆(D)、轻度认知障碍(MCI)和认知正常对照组(CN)患者中的效度。方法:研究对象分别为25例D组、43例MCI组和111例对照CN组。认知评估采用迷你精神状态检查、阿尔茨海默病神经心理学研究联盟和临床痴呆评分。功能评估采用Barthel-Activities of Daily Living, Instrumental Activities of Daily Living,痴呆筛查问卷,K-UPSA-2-VIM。 结果:三组间K-UPSA-2-VIM各子域及总分均有统计学差异。K-UPSA-2-VIM鉴别CN组和MCI组的敏感性为75.7%,特异性为65.1%,曲线下面积(AUC)为0.731(95%可信区间[CI]: 0.641-0.821, p<0.001)。鉴别MCI组和D组的敏感性为76.7%,特异性为64.0%,AUC为0.706 (95% CI: 0.580-0.833, p=0.005)。 结论:K-UPSA-2-VIM可用于评价韩国D合并MCI患者的日常生活功能活动。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Validation of the Measures for Activities of Daily Living Function: the Korean Version of the University of California San Diego Performance-Based Skills Assessment
Objective: The study’s aim was to evaluate the validity of the Korean version of the University of California San Diego Performance- based Skills Assessment, Validation of Intermediate Measures (K-UPSA-2-VIM) in patients with dementia (D), mild cognitive impairment (MCI), and cognitive normal control group (CN). Methods: Study participants were 25 patients with D, 43 patients with MCI, and 111 controls with CN group, respectively. For cognitive assessment, Mini Mental State Examination, Consortium to Establish a Registry for Alzheimer’s Disease neuropsychological battery, and Clinical Dementia Rating were used. For functional assessment, Barthel-Activities of Daily Living, Instrumental Activities of Daily Living, Dementia Screening questionnaire, and K-UPSA-2-VIM were used. Results: Statistically significant differences were observed in all subdomains and total score of the K-UPSA-2-VIM among three cognitive groups. K-UPSA-2-VIM demonstrated 75.7% of sensitivity and 65.1% of specificity, with an area under the curve (AUC) of 0.731 (95% confidence interval [CI]: 0.641-0.821, p<0.001) in discriminating between CN and MCI groups. In discriminating between MCI and D groups, 76.7% of sensitivity and 64.0% of specificity, with an AUC of 0.706 (95% CI: 0.580-0.833, p=0.005) were demonstrated. Conclusion: The K-UPSA-2-VIM is useful to evaluate activities of daily living function in Korean patients with D and MCI.
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