绿茶草药漱口水与0.2%葡萄糖酸氯己定漱口水对牙菌斑变形链球菌抗菌效果的比较研究——一项随机对照试验

Aarcha S Kumar, Mallayya C Hiremath, SK Srinath, Raja Jayadev Nayak, Kala Yadav, Chetana GS
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引用次数: 0

摘要

背景与目的几种化学制剂可以改变口腔菌群,但对口腔组织有不良影响。绿茶茶树含有足够的儿茶素和多酚化合物。具有抗菌、抗氧化、抗炎、抗病毒、抗诱变和抗肿瘤等特性。本临床试验的目的是评估和比较市售的0.5绿茶草药漱口水和0.2葡萄糖酸氯己定漱口水对学龄儿童牙菌斑样本中变形链球菌的抗菌效果。方法将30例健康合作儿童随机分为两组:A组0.2葡萄糖酸氯己定漱口水和B组0.5绿茶漱口水。收集基线和第15天冲洗后菌斑样本。在第0天和第15天进行变形链球菌菌落计数,并对结果进行统计学比较。结果组内配对t检验分析显示,从基线到冲洗后,0.2氯己定组(1.68plusmn0.63 95 CI -1.45至1.77)和绿茶组(0.5 1.54plusmn0.16 95 CI - 1.37至1.69)的变形链球菌计数均显著降低。各组间独立t检验分析均未显示基线和冲洗后的显著差异(p < 0.05)。结论0.2氯己定漱口水与绿茶0.5漱口水对减少变形链球菌数量的效果相同。而0.2氯己定漱口水效果稍好。绿茶漱口水具有不染色、无口感干扰、参与依从性好等优点。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Comparative Evaluation of Antimicrobial Efficacy of Green Tea Herbal Mouth-wash and 0.2% Chlorhexidine Gluconate Mouthwash Against Streptococcus mutans in Dental Plaque - A Randomized Controlled Trial
Background and Aim Several chemical agents can alter the profile of oral microflora but can cause undesirable effects on oral tissues. Green tea Camellia sinensis contains adequate amounts of catechins and polyphenol compounds. It has demonstrated antibacterial antioxidant anti-inflammatory antiviral antimutagenic and anticaries properties.The purpose of this clinical trial was to evaluate and compare the antimicrobial efficacy of commercially available 0.5 green tea herbal mouthwash with 0.2 chlorhexidine gluconate mouthwash against Streptococcus mutans in dental plaque samples of school children. Methods This clinical trial was conducted including thirty healthy cooperative children who were randomly divided into two groups Group A 0.2 Chlorhexidine gluconate mouthwash and Group B 0.5 Green tea mouthwash. Baseline and day 15 post-rinse plaque samples were collected. Streptococcus mutans colony counting was done on day zero and on day 15 and the results were compared statistically.Results Within the group paired t-test analysis showed a significant reduction p lt0.05 of Streptococcus mutans counts from baseline to post-rinse in both 0.2 chlorhexidine 1.68plusmn0.63 95 CI -1.45 to 1.77 and green tea 0.5 1.54plusmn0.16 95 CI - 1.37 to 1.69 groups. Between groups independent t-test analysis did not show any significant difference both at baseline and post-rinse p gt0.05.Conclusion Both 0.2 chlorhexidine mouthwash and green tea 0.5 mouthwash were equally efficient in reducing S. mutans counts. However 0.2 Chlorhexidine mouthwash was marginally better. Green tea mouthwash has the advantage of being non-staining having no taste disturbance and having good participant compliance.
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