Al-Najaf省多囊卵巢综合征妇女血脂和性激素的评价

Q4 Pharmacology, Toxicology and Pharmaceutics
Abdul-Samad U Hassan, Ameer N. K
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引用次数: 0

摘要

背景:影响女性生育年龄的多因素疾病是多囊卵巢综合征(PCOS)。本研究旨在探讨多囊卵巢综合征患者的血脂、性激素和脱氢表雄酮激素的相关性。方法:对45例多囊卵巢综合征(PCOS)育龄期女性的性激素、血脂和脱氢表雄酮(DHEA)激素水平与45例同龄健康女性进行比较。结果:我们的研究结果显示,女性多囊综合征患者甘油三酯参数的平均值±标准差(73.2±147.3 mg/dl)和对照组甘油三酯参数(57.9±123.7 mg/dl)均高于其他参数,差异极显著(p值<0.001)。而其他参数,包括胆固醇、HDL、LDL和VLDL的平均值±标准差,多囊综合征女性高于对照组。结论:生育期越活跃的年龄组,21 ~ 30岁更易发生PCOS。我们的数据显示患者组DHEA与胆固醇、HDL、VLDL之间存在显著相关性。脱氢表雄酮与低密度脂蛋白、脱氢表雄酮与LH、催乳素和睾酮呈正相关。DHEA与FSH呈被动相关(有统计学意义)。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Evaluation of Lipid Profile and Sexual Hormones in Women with Polycystic Ovarian Syndrome at Al-Najaf Province
Background: A multiple-factorial condition influencing females’ reproductive years is polycystic ovarian syndrome (PCOS). This study aims to investigate lipid profiles and sex hormones, and DHEA hormones related to patients suffering from PCOS. Method: In this investigation, the sex hormones, lipid profile and DHEA hormone of 45 females in their reproductive years who were suffering from PCOS were compared to those of 45 women who were healthy and of a similar age. Results: Our results showed that the mean ± standard deviation of triglyceride parameter is higher than others parameters in both women patients with polycystic syndrome (73.2 ± 147.3 mg/dl) and control (57.9 ± 123.7 mg/dl) groups with highly significant difference (p-value < 0.001). While, mean ± standard deviation of other parameters, including cholesterol, HDL, LDL and VLDL, was higher in women with polycystic syndrome than in the control groupe. Conclusion: The more active fertile age group, 21 to 30 years old are more susceptible to the incidence of PCOS. Our data shows a significant correlation between DHEA and cholesterol, HDL, VLDL in the patient group. There is a positive statistical correlation between DHEA and LDL and between DHEA and LH, prolactin, and testosterone. The correlation between DHEA and FSH showed a passive association (statistically significant).
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来源期刊
International Journal of Drug Delivery Technology
International Journal of Drug Delivery Technology Pharmacology, Toxicology and Pharmaceutics-Pharmaceutical Science
CiteScore
0.70
自引率
0.00%
发文量
0
期刊介绍: International Journal of Drug Delivery Technology (IJDDT) provides the forum for reporting innovations, production methods, technologies, initiatives and the application of scientific knowledge to the aspects of pharmaceutics, including controlled drug release systems, drug targeting etc. in the form of expert forums, reviews, full research papers, and short communications.
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