{"title":"Al-Najaf省多囊卵巢综合征妇女血脂和性激素的评价","authors":"Abdul-Samad U Hassan, Ameer N. K","doi":"10.25258/ijddt.13.3.27","DOIUrl":null,"url":null,"abstract":"Background: A multiple-factorial condition influencing females’ reproductive years is polycystic ovarian syndrome (PCOS). This study aims to investigate lipid profiles and sex hormones, and DHEA hormones related to patients suffering from PCOS. Method: In this investigation, the sex hormones, lipid profile and DHEA hormone of 45 females in their reproductive years who were suffering from PCOS were compared to those of 45 women who were healthy and of a similar age. Results: Our results showed that the mean ± standard deviation of triglyceride parameter is higher than others parameters in both women patients with polycystic syndrome (73.2 ± 147.3 mg/dl) and control (57.9 ± 123.7 mg/dl) groups with highly significant difference (p-value < 0.001). While, mean ± standard deviation of other parameters, including cholesterol, HDL, LDL and VLDL, was higher in women with polycystic syndrome than in the control groupe. Conclusion: The more active fertile age group, 21 to 30 years old are more susceptible to the incidence of PCOS. Our data shows a significant correlation between DHEA and cholesterol, HDL, VLDL in the patient group. There is a positive statistical correlation between DHEA and LDL and between DHEA and LH, prolactin, and testosterone. The correlation between DHEA and FSH showed a passive association (statistically significant).","PeriodicalId":13851,"journal":{"name":"International Journal of Drug Delivery Technology","volume":"41 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2023-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Evaluation of Lipid Profile and Sexual Hormones in Women with Polycystic Ovarian Syndrome at Al-Najaf Province\",\"authors\":\"Abdul-Samad U Hassan, Ameer N. K\",\"doi\":\"10.25258/ijddt.13.3.27\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Background: A multiple-factorial condition influencing females’ reproductive years is polycystic ovarian syndrome (PCOS). This study aims to investigate lipid profiles and sex hormones, and DHEA hormones related to patients suffering from PCOS. Method: In this investigation, the sex hormones, lipid profile and DHEA hormone of 45 females in their reproductive years who were suffering from PCOS were compared to those of 45 women who were healthy and of a similar age. Results: Our results showed that the mean ± standard deviation of triglyceride parameter is higher than others parameters in both women patients with polycystic syndrome (73.2 ± 147.3 mg/dl) and control (57.9 ± 123.7 mg/dl) groups with highly significant difference (p-value < 0.001). While, mean ± standard deviation of other parameters, including cholesterol, HDL, LDL and VLDL, was higher in women with polycystic syndrome than in the control groupe. Conclusion: The more active fertile age group, 21 to 30 years old are more susceptible to the incidence of PCOS. Our data shows a significant correlation between DHEA and cholesterol, HDL, VLDL in the patient group. There is a positive statistical correlation between DHEA and LDL and between DHEA and LH, prolactin, and testosterone. The correlation between DHEA and FSH showed a passive association (statistically significant).\",\"PeriodicalId\":13851,\"journal\":{\"name\":\"International Journal of Drug Delivery Technology\",\"volume\":\"41 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-09-25\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"International Journal of Drug Delivery Technology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.25258/ijddt.13.3.27\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"Pharmacology, Toxicology and Pharmaceutics\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"International Journal of Drug Delivery Technology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.25258/ijddt.13.3.27","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Pharmacology, Toxicology and Pharmaceutics","Score":null,"Total":0}
Evaluation of Lipid Profile and Sexual Hormones in Women with Polycystic Ovarian Syndrome at Al-Najaf Province
Background: A multiple-factorial condition influencing females’ reproductive years is polycystic ovarian syndrome (PCOS). This study aims to investigate lipid profiles and sex hormones, and DHEA hormones related to patients suffering from PCOS. Method: In this investigation, the sex hormones, lipid profile and DHEA hormone of 45 females in their reproductive years who were suffering from PCOS were compared to those of 45 women who were healthy and of a similar age. Results: Our results showed that the mean ± standard deviation of triglyceride parameter is higher than others parameters in both women patients with polycystic syndrome (73.2 ± 147.3 mg/dl) and control (57.9 ± 123.7 mg/dl) groups with highly significant difference (p-value < 0.001). While, mean ± standard deviation of other parameters, including cholesterol, HDL, LDL and VLDL, was higher in women with polycystic syndrome than in the control groupe. Conclusion: The more active fertile age group, 21 to 30 years old are more susceptible to the incidence of PCOS. Our data shows a significant correlation between DHEA and cholesterol, HDL, VLDL in the patient group. There is a positive statistical correlation between DHEA and LDL and between DHEA and LH, prolactin, and testosterone. The correlation between DHEA and FSH showed a passive association (statistically significant).
期刊介绍:
International Journal of Drug Delivery Technology (IJDDT) provides the forum for reporting innovations, production methods, technologies, initiatives and the application of scientific knowledge to the aspects of pharmaceutics, including controlled drug release systems, drug targeting etc. in the form of expert forums, reviews, full research papers, and short communications.