双侧胸内动脉移植术:十五年经验

Alexey V. Frolov, Nikita I. Zagorodnikov, Sergey V. Ivanov, Roman S. Tarasov, Leonid S. Barbarash
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摘要

强调双侧胸内动脉(BITA)移植术是直接心肌血运重建最有效的方法之一。然而,尽管世界范围内使用更多的自体动脉导管的趋势,其结果仍然是矛盾的。这项研究涉及了库兹巴斯在冠状动脉疾病手术中使用BITA的超过15年的数据。在分析过程中提出的结果证实需要更积极地使用乳腺内动脉。的目标。通过15年以上的随访分析BITA植入术的远期疗效。方法。该研究包括232例在心脏外科接受冠状动脉旁路移植术(CABG)的患者。所有患者根据单侧或双侧胸内动脉导管的使用情况分为两组。两组纳入相同数量的患者116例(50%)。长期结果是根据超过15年的随访来评估的。结果。在反复心肌血运重建术、卒中等主要心脑血管不良事件以及15年内心肌梗死(MI)、卒中、反复心肌血运重建术或患者死亡等联合终点方面,BITA移植与CABG相当。然而,BITA组在心肌梗死、全因死亡、术后预期寿命更长(p = 0.011)、左室射血分数改善、心绞痛功能等级降低等方面优于CABG组。此外,在本研究中证实,自体动脉导管旁路后冠状动脉粥样硬化的严重程度较低。结论。与CABG相比,BITA是一种安全的手术,然而,它具有更有利的长期临床和血管造影结果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
BILATERAL INTERNAL THORACIC ARTERY GRAFTING: FIFTEEN YEARS OF EXPERIENCE
Highlights Bilateral internal thoracic artery (BITA) grafting is one of the most effective methods of direct myocardial revascularization. However, its results are still contradictory, despite the worldwide trend to use more autogenous arterial conduits. This study involves more than fifteen years of data in the use of BITA in Kuzbass in coronary artery disease surgery. The findings presented in the course of the analysis confirm the need to use both internal mammary arteries more actively. Aim. To analyze long-term results of BITA grafting in terms of more than 15 years follow-up. Methods. The study included 232 patients who were admitted at the Cardiac Surgery Department for coronary artery bypass grafting (CABG). All patients were divided into 2 groups depending on usage of single or bilateral internal thoracic artery conduits. Both groups included an equal number of patients 116 (50%). Long-term results were assessed in terms of more than 15 years follow-up. Results. BITA grafting is comparable with CABG in such major adverse cardiac and cerebrovascular events as repeated myocardial revascularization, stroke, and in combined endpoint such as myocardial infarction (MI), stroke, repeated myocardial revascularization, or patient’s death within 15 years. However, the BITA group is superior to the CABG group in freedom from MI, all-cause deaths, showing a higher life expectancy after surgery (p = 0.011), and improved left ventricular ejection fraction and decreased functional class of angina. Moreover, in the present research it was confirmed that the severity of atherosclerosis in the coronary arteries is lower after bypassing with autogenous arterial conduits. Conclusion. BITA is safe procedure comparable with CABG, however, it has more advantageous long-term clinical and angiographic results.
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