{"title":"摩洛哥一名免疫能力儿童发生疫苗相关麻痹性脊髓灰质炎病例","authors":"Sanae Lemrabet, Abdelkarim Filali-Maltouf, Leila Medraoui, Hicham Oumzil","doi":"10.55522/jmpas.v12i5.5482","DOIUrl":null,"url":null,"abstract":"This article describes the case of a previously healthy immune-competent child who, despite having received full protection against poliomyelitis with OPV, developed severe flaccid paralysis which eventually led to his death. Poliovirus testing of his contacts revealed the presence of Sabin-like type 3 poliovirus in one of them. The patient developed paralysis and respiratory distress and deceased a few months after the onset of paralysis with respiratory failure. This tragic case report demonstrates the emergence of VAPP and emphasizes the significance of early diagnosis of VAPP infections to enhance the clinical management of VAPP-infected patients.","PeriodicalId":16445,"journal":{"name":"Journal of Medical pharmaceutical and allied sciences","volume":"148 19","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2023-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"A case of vaccine associated paralytic poliomyelitis in an immune competent child in Morocco\",\"authors\":\"Sanae Lemrabet, Abdelkarim Filali-Maltouf, Leila Medraoui, Hicham Oumzil\",\"doi\":\"10.55522/jmpas.v12i5.5482\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"This article describes the case of a previously healthy immune-competent child who, despite having received full protection against poliomyelitis with OPV, developed severe flaccid paralysis which eventually led to his death. Poliovirus testing of his contacts revealed the presence of Sabin-like type 3 poliovirus in one of them. The patient developed paralysis and respiratory distress and deceased a few months after the onset of paralysis with respiratory failure. This tragic case report demonstrates the emergence of VAPP and emphasizes the significance of early diagnosis of VAPP infections to enhance the clinical management of VAPP-infected patients.\",\"PeriodicalId\":16445,\"journal\":{\"name\":\"Journal of Medical pharmaceutical and allied sciences\",\"volume\":\"148 19\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-10-31\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Medical pharmaceutical and allied sciences\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.55522/jmpas.v12i5.5482\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Medical pharmaceutical and allied sciences","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.55522/jmpas.v12i5.5482","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
A case of vaccine associated paralytic poliomyelitis in an immune competent child in Morocco
This article describes the case of a previously healthy immune-competent child who, despite having received full protection against poliomyelitis with OPV, developed severe flaccid paralysis which eventually led to his death. Poliovirus testing of his contacts revealed the presence of Sabin-like type 3 poliovirus in one of them. The patient developed paralysis and respiratory distress and deceased a few months after the onset of paralysis with respiratory failure. This tragic case report demonstrates the emergence of VAPP and emphasizes the significance of early diagnosis of VAPP infections to enhance the clinical management of VAPP-infected patients.