流变学对骨组织工程用陶瓷支架制备的影响

IF 0.7 4区 材料科学 Q4 METALLURGY & METALLURGICAL ENGINEERING
Jameer K. Bagwan, Bharatkumar B. Ahuja
{"title":"流变学对骨组织工程用陶瓷支架制备的影响","authors":"Jameer K. Bagwan, Bharatkumar B. Ahuja","doi":"10.1515/ijmr-2022-0245","DOIUrl":null,"url":null,"abstract":"Abstract Bone tissue is the second most affected organ in the human body after blood. Tissue engineering is the area whereby a scaffold is used to regenerate the lost bone. However, the scaffold’s effectiveness is primarily based on the material and the fabrication process. The patient-specific structures are affected because of the fabrication process used to fabricate the scaffold as per requirement. In this regard, rheology plays an important role in the fabrication of the patient-specific scaffold, and it is a study of the flow of ink. This primarily affects both the conventional as well as the non-conventional fabrication processes. In this paper, the scaffold and bone tissue engineering, the different fabrication processes, and the importance of the rheological characterization are presented. In addition to this, the rheological properties of the developed HA/β-TCP composite slurry are evaluated for the extrusion-based additive manufacturing process. The developed ink’s rheological properties show that the flow behavior index of about 0.0497 ± 0.009, minimum flow stress required to make the ink flow of about 51.076 Pa at a strain rate of 0.111 %, and shape retention upto 75 % after 175 s are obtained. Also, different orientations are 3D printed using the developed slurry.","PeriodicalId":14079,"journal":{"name":"International Journal of Materials Research","volume":"121 1","pages":"0"},"PeriodicalIF":0.7000,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"The influence of rheology in the fabrication of ceramic-based scaffold for bone tissue engineering\",\"authors\":\"Jameer K. Bagwan, Bharatkumar B. Ahuja\",\"doi\":\"10.1515/ijmr-2022-0245\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Abstract Bone tissue is the second most affected organ in the human body after blood. Tissue engineering is the area whereby a scaffold is used to regenerate the lost bone. However, the scaffold’s effectiveness is primarily based on the material and the fabrication process. The patient-specific structures are affected because of the fabrication process used to fabricate the scaffold as per requirement. In this regard, rheology plays an important role in the fabrication of the patient-specific scaffold, and it is a study of the flow of ink. This primarily affects both the conventional as well as the non-conventional fabrication processes. In this paper, the scaffold and bone tissue engineering, the different fabrication processes, and the importance of the rheological characterization are presented. In addition to this, the rheological properties of the developed HA/β-TCP composite slurry are evaluated for the extrusion-based additive manufacturing process. The developed ink’s rheological properties show that the flow behavior index of about 0.0497 ± 0.009, minimum flow stress required to make the ink flow of about 51.076 Pa at a strain rate of 0.111 %, and shape retention upto 75 % after 175 s are obtained. Also, different orientations are 3D printed using the developed slurry.\",\"PeriodicalId\":14079,\"journal\":{\"name\":\"International Journal of Materials Research\",\"volume\":\"121 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.7000,\"publicationDate\":\"2023-10-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"International Journal of Materials Research\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1515/ijmr-2022-0245\",\"RegionNum\":4,\"RegionCategory\":\"材料科学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"METALLURGY & METALLURGICAL ENGINEERING\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"International Journal of Materials Research","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1515/ijmr-2022-0245","RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"METALLURGY & METALLURGICAL ENGINEERING","Score":null,"Total":0}
引用次数: 0

摘要

骨组织是人体中仅次于血液的第二大受影响器官。组织工程是使用支架来再生丢失的骨骼的领域。然而,支架的有效性主要取决于材料和制造过程。由于按照要求制造支架的制造过程,患者特定的结构受到影响。在这方面,流变学在患者特异性支架的制造中起着重要作用,它是对墨水流动的研究。这主要影响传统和非传统的制造工艺。本文介绍了支架和骨组织工程,不同的制造工艺,以及流变学表征的重要性。除此之外,还对开发的HA/β-TCP复合浆料的流变特性进行了评估,以用于基于挤出的增材制造工艺。制备的油墨流变性能表明,该油墨的流动性能指数约为0.0497±0.009,在应变率为0.111%时,使油墨流动速度约为51.076 Pa所需的最小流动应力,175 s后的形状保留率高达75%。此外,使用开发的浆液3D打印不同的方向。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The influence of rheology in the fabrication of ceramic-based scaffold for bone tissue engineering
Abstract Bone tissue is the second most affected organ in the human body after blood. Tissue engineering is the area whereby a scaffold is used to regenerate the lost bone. However, the scaffold’s effectiveness is primarily based on the material and the fabrication process. The patient-specific structures are affected because of the fabrication process used to fabricate the scaffold as per requirement. In this regard, rheology plays an important role in the fabrication of the patient-specific scaffold, and it is a study of the flow of ink. This primarily affects both the conventional as well as the non-conventional fabrication processes. In this paper, the scaffold and bone tissue engineering, the different fabrication processes, and the importance of the rheological characterization are presented. In addition to this, the rheological properties of the developed HA/β-TCP composite slurry are evaluated for the extrusion-based additive manufacturing process. The developed ink’s rheological properties show that the flow behavior index of about 0.0497 ± 0.009, minimum flow stress required to make the ink flow of about 51.076 Pa at a strain rate of 0.111 %, and shape retention upto 75 % after 175 s are obtained. Also, different orientations are 3D printed using the developed slurry.
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
CiteScore
1.30
自引率
12.50%
发文量
119
审稿时长
6.4 months
期刊介绍: The International Journal of Materials Research (IJMR) publishes original high quality experimental and theoretical papers and reviews on basic and applied research in the field of materials science and engineering, with focus on synthesis, processing, constitution, and properties of all classes of materials. Particular emphasis is placed on microstructural design, phase relations, computational thermodynamics, and kinetics at the nano to macro scale. Contributions may also focus on progress in advanced characterization techniques. All articles are subject to thorough, independent peer review.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信