尼日利亚东南部某高等教育机构糖尿病视网膜病变患病率及危险因素

Michael Chinweuba Abonyi, Theophilus Ejiofor Ugwu, Christian Chukwuemeka Eze
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摘要

本研究旨在确定在尼日利亚东南部埃努古一家三级卫生中心就诊的受试者中糖尿病视网膜病变(DR)的患病率和危险因素。这项横断面研究是在尼日利亚埃努古的转诊中心埃努古州立大学教学医院进行的为期三天的筛查活动中对147名糖尿病患者进行的。共招募147例糖尿病患者,接受直接眼底镜检查和裂隙灯检查糖尿病(DM)引起的眼部异常。还获得了每个受试者的社会人口学、临床和人体测量指标。本研究DR患病率为18.7%。血糖控制不良(HbA1c>7%)与DR患病率呈正相关。然而,DR与已知危险因素(包括糖尿病持续时间延长、高血压、体重指数(BMI)和中心性肥胖、水果摄入、饮酒和吸烟)之间没有显著关联。DR是糖尿病的一种严重的微血管并发症,存在于相当数量的糖尿病患者中。强烈建议通过最佳血糖控制进行一级预防,以防止大部分不可逆的视网膜损伤和视力丧失。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Prevalence and risk factors for Diabetic Retinopathy in a tertiary institution in South Eastern Nigeria
This study aimed to determine the prevalence and risk factors for Diabetic Retinopathy (DR) in subjects attending a tertiary health center in Enugu, Southeast Nigeria. This cross-sectional study was carried out during a three-day screening exercise among 147 diabetic patients at Enugu State University Teaching Hospital, a referral center in Enugu, Nigeria. A total of 147 patients with diabetes were recruited, and underwent direct fundoscopy as well as slit lamp examination for Diabetes Mellitus (DM)-induced ocular abnormalities. Socio-demographic, clinical and anthropometric indices were also obtained from each subject. The prevalence of DR was 18.7% in this study. Poor glycemic control (HbA1c>7%) was positively associated with the prevalence of DR. There was, however, no significant association between DR and known risk factors, including prolonged duration of DM, hypertension, Body Mass Index (BMI) and central obesity, fruit intake, alcohol use, and smoking. DR, a serious microvascular complication of DM, is present in a significant number of diabetic subjects. Primary prevention, by optimal glycemic control, is highly recommended to prevent largely irreversible retinal damage and visual loss.
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