诺玛病破坏眶骨致致盲:来自尼日利亚西北部索科托诺玛儿童医院的病例系列

Bala M, Abubakar AB
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摘要

背景:坏疽性口炎是一种在发病过程中迅速破坏口面部组织和邻近结构的传染病。本研究旨在介绍一系列因坏疽性口炎破坏眶骨而失明的病例,并强调其治疗的重要方面。患者和方法:本研究是在尼日利亚西北部索科托诺玛儿童医院进行的为期2年的研究期间,对12名因坏疽性口炎并发失明的患者进行观察和治疗的病例系列。记录社会人口学变量、主诉、视力、调查和治疗情况。数据分析采用IBM SPSS version 25。结果:男性4例(33.3%),女性8例(66.7%),年龄4 ~ 15岁,平均±SD为7.5±3.3岁。到我们医院就诊前的发病时间范围为2周到4个月。眼科检查发现眼球破坏,脓性分泌物无光感。所有患者均存在贫血和营养不良,微生物培养和敏感性(MCS)未见生长。对患者进行优化,然后进行固骨切除和拔牙。对患者进行监测直至症状消退。结论:坏疽性口炎可迅速向眼眶扩散,并发视力丧失。然而,在咨询眼科医生的情况下,积极的医疗和手术干预可以导致症状的早期解决,并防止可能导致失明的进一步扩散。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Blindness Secondary to Noma Destruction of Orbital Bone: Case Series from Noma Children Hospital Sokoto, Northwest Nigeria
Background: Noma is an infectious disease that rapidly destroys orofacial tissues and neighboring structures in its fulminating course. This study aimed to present a case series of blindness as a result of Noma destruction of the orbital bone and highlight the important aspect of its management. Patients and methods: This was a case series of 12 patients seen and managed for Noma with associated blindness over 2 years study period at Noma Children Hospital Sokoto, Northwest Nigeria. Sociodemographic variables, presenting complaints, presenting visual acuity, investigations, and, the treatment done was recorded. Data were analyzed using IBM SPSS version 25. Result: There were 4 (33.3%) males and, 8 (66.7%) females in the age range of 4-15 years with a mean±SD of 7.5±3.3years. The time range of onset before presentation to our facility was 2 weeks to 4 months. Ophthalmic examination revealed a destroyed globe and purulent discharge with no light perception in all the patients. Anemia and malnutrition were present and, microbiological culture and sensitivity (MCS) yielded no growth in all the patients. Patients were optimized, then later had sequestrectomy and, teeth extraction. Monitoring of patients was done until symptoms resolution. Conclusion: Noma is capable of spreading rapidly to the orbit, causing loss of vision as a complication. However, aggressive medical and surgical intervention in consultation with an ophthalmologist can result in early resolution of symptoms and prevent further spread that may lead to blindness.
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