接受改良滑动气管成形术的先天性气管狭窄患者:单中心技术与长期发病率和死亡率

Ryaan EL-Andari MD , Rami Zibdawi BSc, MSc , Paula Holinski MD , John Koller MD , Chloe Joynt MD , Nee Khoo MBChB , Laurance Lequier MD , Hamdy El-Hakim MD , Mohammed Al Aklabi FRCSC, MD
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引用次数: 0

摘要

背景先天性气管畸形非常罕见,但往往危及生命。有关气管重建治疗先天性气管狭窄的结果的数据有限。方法纳入2012年1月1日至2022年8月31日期间接受长段气管或支气管重建术的所有儿科患者。主要结果是死亡率,次要结果包括再次手术和术后发病率。结果纳入的 33 例患者在进行气管成形术或支气管成形术时的年龄从 1 天到 12 岁不等(平均 8.5 个月),其中 5 例患者进行了离体气管重建术。术前最常见的合并症包括动脉导管未闭(30.3%)、房间隔缺损(27.3%)和早产(24.2%)。术后随访期间无死亡病例。所有患者的气管重建均获得成功,没有患者需要再次进行气管手术。共有14名患者(42.4%)需要在术后进行球囊扩张,3名患者(9.1%)需要在气管修复后进行支气管修补,2名患者(6.1%)需要进行支气管镜下气管清创术。大多数患者术前有合并症,并伴有先天性心脏缺陷。虽然气管重建手术仍然很复杂,术后发病率和死亡率也很高,但我们的单中心研究结果表明,这一领域在不断进步,这些患者的术后效果也在不断改善。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Congenital Tracheal Stenosis Patients Undergoing Modified Slide Tracheoplasty: Single-Centre Technique and Long-Term Morbidity and Mortality

Background

Congenital malformations of the trachea are rare but often life-threatening. Limited data have been published on the outcomes of tracheal reconstruction for congenital tracheal stenosis. We sought to describe the outcomes of patients undergoing tracheal reconstruction over 10 years at our centre.

Methods

All paediatric patients who underwent long-segment tracheal or bronchial reconstruction from January 1, 2012, to August 31, 2022, were included. The primary outcome was mortality, and secondary outcomes included reoperation and postoperative morbidity. Patients were followed up to 10 years.

Results

Thirty-three patients with ages ranging from 1 day to 12 years (mean 8.5 months) at the time of tracheoplasty or bronchoplasty were included, with 5 patients undergoing off-pump tracheal reconstruction. The most common preoperative comorbidities included patent ductus arteriosus (30.3%), atrial septal defect (27.3%), and prematurity (24.2%). There were no deaths postoperatively within the follow-up period. All patients experienced successful reconstruction with no patients requiring reoperation of the trachea. A total of 14 patients (42.4%) required postoperative balloon dilation, 3 (9.1%) required bronchial repair after tracheal repair, and 2 (6.1%) required bronchoscopic tracheal debridement.

Conclusions

This single-centre retrospective study provides a large cohort of congenital tracheal reconstruction patients with a survival rate of 100%, experiencing no mortality during follow-up. The majority of patients had preoperative comorbidities and concomitant congenital cardiac defects. Although tracheal reconstruction continues to be complex with significant postoperative morbidity and mortality, the results of our single-centre study demonstrate the continual advancement of this field and the evolving improvement of postoperative outcomes for these patients.

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