耳鸣的发病机制

Q4 Medicine
Francesca Yoshie RUSSO, Antonio GRECO
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引用次数: 0

摘要

耳鸣是一种影响很大一部分人群的病理状况,近年来在了解其生理病理方面取得了很大进展,然而,在各种发病假说中确定一个独特的机制仍然是一个挑战。证据获取:根据PRISMA指南,在以下电子数据库:PubMed/Medline、Scopus和Web of Science中进行文献综述,没有时间限制,截止到2022年12月31日。随后执行了额外的手动搜索。证据综合:慢性耳鸣可能是许多外周和中枢动力学的结果,这些动力学有助于稳定一种触发可能是短暂的现象。结论:确定耳鸣的病因可以更好地治疗耳鸣,在许多情况下,耳鸣的发病可能与特定的情况或疾病有关,如听觉减退、衰老、听觉创伤、使用耳毒性药物、耳科或全身性疾病,但也可能与抑郁或头部创伤有关。然而,耳鸣在某些个体中成为慢性耳鸣的机制尚不完全清楚。有证据表明,中枢神经系统的作用是至关重要的维持。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Etiopathogenesis of tinnitus
INTRODUCTION: Tinnitus is a pathological condition that affects a large portion of the population, and in recent years great progresses have been made in understanding its physiopathology, however, identify a unique mechanism among the various etiopathogenetic hypotheses still remains a challenge.EVIDENCE ACQUISITION: A Review of literature was performed following PRISMA guidelines, in the following electronic data base: PubMed/Medline, Scopus and Web of Science, without time limits, until December 31st 2022. An additional manual search was performed afterwards.EVIDENCE SYNTHESIS: It is probable that chronic tinnitus is the result of numerous peripheral and central dynamics, which contribute to stabilizing a phenomenon whose trigger can be transient.CONCLUSIONS: The identification of an etiology for tinnitus could allow a better therapeutic management, in many cases the onset of tinnitus can be associated with a specific circumstance or disease, such as hypoacusis, ageing, acoustic trauma, use of ototoxic drugs, otological or systemic diseases, but also depression or head trauma. However, the mechanisms by which tinnitus becomes chronic in some individuals are not fully understood. There is evidence that the role of the central nervous system is crucial for maintenance.
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来源期刊
Otorhinolaryngology Clinics
Otorhinolaryngology Clinics Medicine-Otorhinolaryngology
CiteScore
0.10
自引率
0.00%
发文量
37
期刊介绍: Otorhinolaryngology Clinics: An International Journal is an International periodical devoted at exploring connections between clinical experience and world literature, and understanding of various pathologies and diseases related to the ear, nose and throat. Issues of recent advancements and research related to disease, illness, health and medical science are examined through various evidence-based clinical research studies. This journal proposes to serve as a collection of clinical notes, with an international perspective, along with the recent advances for postgraduates and consultants. The readership for this journal would include a wide variety of healthcare professionals, such as otolaryngologists, head and neck surgeons, ENT nurses as well as scholars and academicians in the field of medicine, trauma, surgery, etc. This journal aims to encourage the analysis of clinical data from various centers all over the world using standardized protocols to develop an international consensual perspective on the management of disorders related to the field of otorhinolaryngology. Recently, we have introduced "Case Reports", "How I Do It" and "Original Research" categories in the process of expanding the scope of the journal. Thisis a peer-reviewed journal of which three issues would be published each year. Each future issue will cover a different topic of special interest in the field of otorhinolaryngology and head and neck surgery. This issue is the first of its kind dedicated to "anesthesia in otorhinolaryngology" and contains a compilation of articles by experienced anesthesiologists dealing with a large volume of ENT and related surgeries. In each issue, the editors give their perspective based on the submitted articles. All non invited articles are peer-reviewed. Peer-revieweing helps in providing unbiased, independent, critical assessment of the results of the research study in question including the scientific process.
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