{"title":"糖尿病足溃疡:生理学,疾病,市场分析,治疗","authors":"Kafadarian Lina, Tawil Bill","doi":"10.15406/jabb.2023.10.00335","DOIUrl":null,"url":null,"abstract":"Diabetic foot ulcers (DFU) are a common, yet preventable complication of diabetes that can lead to serious health risks if left untreated. DFUs pose a significant challenge on not only the affected individual but also the community due to their complex pathophysiology and limited, often insufficient treatment options. This paper will provide a holistic review on diabetic foot ulcers, elaborating on their physiology, the current and projected market sizes, and discussing available treatments and products. Tissue engineering is becoming a quite impactful option for treating diabetic wounds, and is the central focus of this review. Additionally, this paper presents pipeline products, as well as a novel product that utilizes the core concepts of regenerative medicine and innovative technology and thus has the potential to overcome many of the limitations associated with existing therapies. Overall, this review serves as a valuable resource for healthcare professionals and researchers interested in diabetic foot ulcers, offering insights into the current state of knowledge and presenting a promising approach that could revolutionize the field","PeriodicalId":15033,"journal":{"name":"Journal of Applied Biotechnology & Bioengineering","volume":"47 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2023-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Diabetic foot ulcers: physiology, disease, market analysis, treatments\",\"authors\":\"Kafadarian Lina, Tawil Bill\",\"doi\":\"10.15406/jabb.2023.10.00335\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Diabetic foot ulcers (DFU) are a common, yet preventable complication of diabetes that can lead to serious health risks if left untreated. DFUs pose a significant challenge on not only the affected individual but also the community due to their complex pathophysiology and limited, often insufficient treatment options. This paper will provide a holistic review on diabetic foot ulcers, elaborating on their physiology, the current and projected market sizes, and discussing available treatments and products. Tissue engineering is becoming a quite impactful option for treating diabetic wounds, and is the central focus of this review. Additionally, this paper presents pipeline products, as well as a novel product that utilizes the core concepts of regenerative medicine and innovative technology and thus has the potential to overcome many of the limitations associated with existing therapies. Overall, this review serves as a valuable resource for healthcare professionals and researchers interested in diabetic foot ulcers, offering insights into the current state of knowledge and presenting a promising approach that could revolutionize the field\",\"PeriodicalId\":15033,\"journal\":{\"name\":\"Journal of Applied Biotechnology & Bioengineering\",\"volume\":\"47 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-08-10\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Applied Biotechnology & Bioengineering\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.15406/jabb.2023.10.00335\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Applied Biotechnology & Bioengineering","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.15406/jabb.2023.10.00335","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Diabetic foot ulcers (DFU) are a common, yet preventable complication of diabetes that can lead to serious health risks if left untreated. DFUs pose a significant challenge on not only the affected individual but also the community due to their complex pathophysiology and limited, often insufficient treatment options. This paper will provide a holistic review on diabetic foot ulcers, elaborating on their physiology, the current and projected market sizes, and discussing available treatments and products. Tissue engineering is becoming a quite impactful option for treating diabetic wounds, and is the central focus of this review. Additionally, this paper presents pipeline products, as well as a novel product that utilizes the core concepts of regenerative medicine and innovative technology and thus has the potential to overcome many of the limitations associated with existing therapies. Overall, this review serves as a valuable resource for healthcare professionals and researchers interested in diabetic foot ulcers, offering insights into the current state of knowledge and presenting a promising approach that could revolutionize the field