维生素A——北欧营养建议2023的范围审查

IF 3.5 4区 医学 Q2 FOOD SCIENCE & TECHNOLOGY
Thomas Olsen, Ulf H. Lerner
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引用次数: 0

摘要

维生素A指的是一组具有视黄醇活性的脂溶性化合物,包括全反式视黄醇和维生素A原类胡萝卜素。生物活性化合物包括视网膜和全反式维甲酸,在视力、免疫功能、生长发育等方面具有重要作用。在当前的范围审查中进行的文献检索中,总共有7篇与设定维生素a的推荐每日摄入量相关的出版物。总共有6篇出版物评估了血清视黄醇和/或膳食维生素a摄入量与骨折风险(n = 2)、癌症(n = 3)和减肥手术后维生素a缺乏(n = 1)的关系。欧洲食品安全管理局(EFSA)的另一份报告包含了更新的平均需取量。基于结果的系统评价和荟萃分析显示,维生素A摄入量和血清视黄醇与髋部骨折风险呈正相关。癌症和肥胖之间存在微弱或不确定的关联。2015年,欧洲食品安全局发布了一份关于膳食维生素A摄入量的最新估计平均需要量和人口参考摄入量的出版物。欧洲食品安全局的建议和估计的平均需要量是基于欧洲参考人口,体重来源于假设的身体质量指数22,这可能太低,不能代表北欧和波罗的海的人口,因此导致估计的平均需要量和建议量较低。总之,关于维生素A和健康结果的新的基于结果的数据有限。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Vitamin A – a scoping review for Nordic nutrition Recommendations 2023
Vitamin A refers to a group of fat-soluble compounds with retinol activity, including all-trans retinol and pro-vitamin A carotenoids. Bioactive compounds include retinal and all-trans retinoic acid with important functions in vision, immune function, growth, and development. The literature search that was performed for the current scoping review yielded a total of seven publications relevant to setting the recommended daily intake for vitamin A. In total, six publications assessed the relationship of serum retinol and/or dietary vitamin A intake with fracture risk (n = 2), cancer (n = 3), and deficiency after bariatric surgery (n = 1). One additional report by the European Food Safety Administration (EFSA) with updated average requirements was included. The outcomes-based systematic reviews and meta-analyses showed positive associations for vitamin A intake and serum retinol with risk of hip fracture. Weak or inconclusive associations were observed for cancer or obesity. One publication by EFSA with updated estimated average requirements and population reference intakes for dietary vitamin A intakes was published in 2015. The EFSA recommendations and estimated average requirements are based on a European reference population, with body weights derived from an assumed body mass index of 22, which might be too low and not representative of the Nordic and Baltic populations, and consequently resulting in lower estimated average requirements and recommendations. In conclusion, there were limited new outcomes-based data for vitamin A and health outcomes.
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来源期刊
Food & Nutrition Research
Food & Nutrition Research FOOD SCIENCE & TECHNOLOGY-NUTRITION & DIETETICS
CiteScore
5.20
自引率
9.10%
发文量
47
审稿时长
14 weeks
期刊介绍: Food & Nutrition Research is a peer-reviewed journal that presents the latest scientific research in various fields focusing on human nutrition. The journal publishes both quantitative and qualitative research papers. Through an Open Access publishing model, Food & Nutrition Research opens an important forum for researchers from academic and private arenas to exchange the latest results from research on human nutrition in a broad sense, both original papers and reviews, including: * Associations and effects of foods and nutrients on health * Dietary patterns and health * Molecular nutrition * Health claims on foods * Nutrition and cognitive functions * Nutritional effects of food composition and processing * Nutrition in developing countries * Animal and in vitro models with clear relevance for human nutrition * Nutrition and the Environment * Food and Nutrition Education * Nutrition and Economics Research papers on food chemistry (focus on chemical composition and analysis of foods) are generally not considered eligible, unless the results have a clear impact on human nutrition. The journal focuses on the different aspects of nutrition for people involved in nutrition research such as Dentists, Dieticians, Medical doctors, Nutritionists, Teachers, Journalists and Manufacturers in the food and pharmaceutical industries.
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