治疗自身免疫性疾病中的间质性肺病（ILD）：类风湿性关节炎和特发性炎症性肌炎

Q3 Health Professions

Revista Colombiana de Reumatologia Pub Date : 2024-04-01 DOI:10.1016/j.rcreu.2023.07.004

Mayra Mejía , Daphne Rivero-Gallegos , Jorge Rojas-Serrano

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引用次数: 0

摘要

本文将介绍与类风湿性关节炎（RA）和炎症性肌病（IIM）等系统性自身免疫疾病相关的间质性肺病的基本治疗方法。由于类风湿性关节炎的疾病活动得到了更严格的控制，类风湿性关节炎相关性间质性肺病（RA-ILD）的预后最近有所改善。本文介绍了甲氨蝶呤对 RA-ILD 的影响的最新证据，甲氨蝶呤可改善 RA-ILD 的预后。现有的替代疗法包括使用抗纤维化药物。在治疗与抗合成酶综合征相关的间质性肺病（ASSD-ILD）和抗MDA5相关的ILD时，提到了免疫抑制和抗纤维化药物治疗的相关方面。

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The treatment of interstitial lung disease (ILD) in the context of autoimmune diseases: Rheumatoid arthritis and idiopathic inflammatory myositis

This article will mention the essential aspects of managing ILD associated with systemic autoimmune diseases such as rheumatoid arthritis (RA) and inflammatory myopathies (IIM). The prognosis of rheumatoid arthritis-associated interstitial lung disease (RA-ILD) has recently improved because of tighter control of RA disease activity. This article presents recent evidence of the effect of methotrexate on RA-ILD, which is associated with a better prognosis. The available alternatives include the use of anti-fibrotic drugs. In managing interstitial lung disease related to anti-synthetase syndrome (ASSD-ILD) and anti-MDA5-associated ILD, immunosuppression and anti-fibrotic drug regimens are relevant aspects mentioned.

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来源期刊

Revista Colombiana de Reumatologia Medicine-Rheumatology

CiteScore

0.80

自引率

0.00%

发文量

期刊介绍： The Colombian Journal of Rheumatology (Revista Colombiana de Reumatología) is the official organ of the Colombian Association of Rheumatology (Asociación Colombiana de Reumatología) and the Central American, Caribbean and Andean Association of Rheumatology (Asociación Centroamericana Caribe Andina de Reumatología) - ACCA. It was created in December 1993 with the purpose of disseminating scientific information derived from primary and secondary research and presenting cases coming from the practice of Rheumatology in Latin America. Since its foundation, the Journal has been characterized by its plurality with subjects of all rheumatic and osteomuscular pathologies, in the form of original articles, historical articles, economic evaluations, and articles of reflection and education in Medicine. It covers an extensive area of topics ranging from the broad spectrum of the clinical aspects of rheumatology and related areas in autoimmunity (both in pediatric and adult pathologies), to aspects of basic sciences. It is an academic tool for the different members of the academic and scientific community at their different levels of training, from undergraduate to post-doctoral degrees, managing to integrate all actors inter and trans disciplinarily. It is intended for rheumatologists, general internists, specialists in related areas, and general practitioners in the country and abroad. It has become an important space in the work of all rheumatologists from Central and South America.