A review on medicinal plants containing glycosides

Plant-active metabolites are under intensive examination around the world to supplement the drugs with minimal side effects. Thus, there is vast potential to explore the possible medicine from plant sources. Cardiac glycosides are a unique group of secondary metabolites that are considered one of the most useful drugs in therapeutics. In this review, cardiac glycosides and their analogs are presented. The structure and distribution in plants, as well as structure elucidations, synthetic routes, and chemical analysis, are shown. In addition, the pharmacological activities, mode of action studies, and structure-activity relationships are cardiac glycosides.