{"title":"七氟醚对冠状动脉搭桥患者左心室功能的影响:一项随机试验","authors":"None Chanjuan Gong, None Xiaokai Zhou, None Yin Fang, None Yanjuan Zhang, None Linjia Zhu, None Zhengnian Ding","doi":"10.7555/jbr.37.20230173","DOIUrl":null,"url":null,"abstract":"The present study aimed to dynamically observe the segmental and global myocardial movements of the left ventricle during coronary artery bypass grafting (CABG) using transesophageal speckle-tracking echocardiography, and to assess the impact of sevoflurane on cardiac function. Sixty-four patients scheduled for the off-pump CABG were randomly divided into a sevoflurane-based anesthesia (AS) group and a propofol-based total intravenous anesthesia (AA) group. The AS group demonstrated a higher absolute value of left ventricular (LV) global longitudinal strain (GLS) than the AA group at both T<sub>1</sub> (after harvesting all grafts and before coronary anastomosis) and T<sub>2</sub> (30 min after completing all coronary anastomoses) (<i>P</i> < 0.05). Moreover, strain improvement in the segment with the highest preoperative strain was significantly reduced in the AS group, compared with the AA group at both T<sub>1</sub> and T<sub>2</sub> (<i>P</i> < 0.01). The flow of the left internal mammary artery-left anterior descending artery graft was superior, and the postoperative concentration of troponin T (cTnT) decreased rapidly in the AS group compared with the AA group (<i>P</i> < 0.05). Compared with total intravenous anesthesia, sevoflurane resulted in significantly higher GLS, stroke volume, and cardiac output. Sevoflurane also led to an amelioration in the condition of the arterial graft. Furthermore, sevoflurane significantly reduced strain improvement in the segmental myocardium with a high preoperative strain value. The findings need to be replicated in large studies.","PeriodicalId":100807,"journal":{"name":"Journal of Nanjing Medical University","volume":"46 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Effects of sevoflurane on left ventricular function by speckle-tracking echocardiography in coronary bypass patients: A randomized trial\",\"authors\":\"None Chanjuan Gong, None Xiaokai Zhou, None Yin Fang, None Yanjuan Zhang, None Linjia Zhu, None Zhengnian Ding\",\"doi\":\"10.7555/jbr.37.20230173\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"The present study aimed to dynamically observe the segmental and global myocardial movements of the left ventricle during coronary artery bypass grafting (CABG) using transesophageal speckle-tracking echocardiography, and to assess the impact of sevoflurane on cardiac function. Sixty-four patients scheduled for the off-pump CABG were randomly divided into a sevoflurane-based anesthesia (AS) group and a propofol-based total intravenous anesthesia (AA) group. The AS group demonstrated a higher absolute value of left ventricular (LV) global longitudinal strain (GLS) than the AA group at both T<sub>1</sub> (after harvesting all grafts and before coronary anastomosis) and T<sub>2</sub> (30 min after completing all coronary anastomoses) (<i>P</i> < 0.05). Moreover, strain improvement in the segment with the highest preoperative strain was significantly reduced in the AS group, compared with the AA group at both T<sub>1</sub> and T<sub>2</sub> (<i>P</i> < 0.01). The flow of the left internal mammary artery-left anterior descending artery graft was superior, and the postoperative concentration of troponin T (cTnT) decreased rapidly in the AS group compared with the AA group (<i>P</i> < 0.05). Compared with total intravenous anesthesia, sevoflurane resulted in significantly higher GLS, stroke volume, and cardiac output. Sevoflurane also led to an amelioration in the condition of the arterial graft. Furthermore, sevoflurane significantly reduced strain improvement in the segmental myocardium with a high preoperative strain value. The findings need to be replicated in large studies.\",\"PeriodicalId\":100807,\"journal\":{\"name\":\"Journal of Nanjing Medical University\",\"volume\":\"46 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Nanjing Medical University\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.7555/jbr.37.20230173\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Nanjing Medical University","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.7555/jbr.37.20230173","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Effects of sevoflurane on left ventricular function by speckle-tracking echocardiography in coronary bypass patients: A randomized trial
The present study aimed to dynamically observe the segmental and global myocardial movements of the left ventricle during coronary artery bypass grafting (CABG) using transesophageal speckle-tracking echocardiography, and to assess the impact of sevoflurane on cardiac function. Sixty-four patients scheduled for the off-pump CABG were randomly divided into a sevoflurane-based anesthesia (AS) group and a propofol-based total intravenous anesthesia (AA) group. The AS group demonstrated a higher absolute value of left ventricular (LV) global longitudinal strain (GLS) than the AA group at both T1 (after harvesting all grafts and before coronary anastomosis) and T2 (30 min after completing all coronary anastomoses) (P < 0.05). Moreover, strain improvement in the segment with the highest preoperative strain was significantly reduced in the AS group, compared with the AA group at both T1 and T2 (P < 0.01). The flow of the left internal mammary artery-left anterior descending artery graft was superior, and the postoperative concentration of troponin T (cTnT) decreased rapidly in the AS group compared with the AA group (P < 0.05). Compared with total intravenous anesthesia, sevoflurane resulted in significantly higher GLS, stroke volume, and cardiac output. Sevoflurane also led to an amelioration in the condition of the arterial graft. Furthermore, sevoflurane significantly reduced strain improvement in the segmental myocardium with a high preoperative strain value. The findings need to be replicated in large studies.