阿姆叶的抗菌作用

Vikas Sharma, Arti Heer, Navneet Kour, Shivangi Sharma
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引用次数: 0

摘要

采用琼脂孔扩散法,研究了木桉叶甲醇提取物对2株革兰氏阳性菌(MTCC2389、MTCC7443)和3株革兰氏阴性菌(MTCC4821、MTCC2127、MTCC7162)的抑菌效果。采用连续微量稀释法(MIC)和琼脂孔扩散法对植物提取物进行敏感性试验。该提取物对(17.6 mm)、(16.5 mm)和(16.2 mm)的抑制区最大。然而,对(15.5 mm)和(15 mm)也有活性报道。采用不同浓度(10μl和20μl)的提取物,与标准药氯霉素(5μg)的最低抑菌浓度(MIC)在62.5 ~ 2000 μg/ml之间进行比较。甲醇提取物的最小抑制浓度为550 μg/ml,表明其具有一定的抗菌潜力和新抗生素的来源。因此,药用植物正在寻找进入药物、中性药物和食品补充剂的途径,这些药物可能对化疗有用,以控制传染病。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Antibacterial efficacy of amla leaves
The present study was carried out to evaluate antibacterial potential of methanolic extract from amla leaves via agar-well diffusion method against two gram positive ( subtilis MTCC2389, MTCC7443) and three gram negative (MTCC4821, MTCC2127, MTCC7162) strains. Susceptibility of plant extract was tested by serial microdilution method (MIC) and agar well diffusion method was determined. The extract showed maximum zone of inhibition against (17.6 mm) followed by (16.5 mm) and (16.2 mm). However, activity was also reported against (15.5 mm) and (15 mm). The different concentrations of extract (10μl and 20μl) were used and the minimum inhibitory concentration (MIC) ranging from 62.5 to 2000 μg/ml was compared with the standard drug Chloramphenicol (5μg). The MIC of methanolic extract was found 550 μg/ml against and The results of present study revealed that leaves of amla possesses antibacterial potential and source of new antibiotics. Therefore, medicinal plants are finding their way into pharmaceuticals, neutralceuticals and food Supplements that could be useful in chemotherapy to control infectious diseases.
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