Michael T. Simpson MD , Mateusz Kachel MD , Robert C. Neely MD , W. Clinton Erwin MD , Aleena Yasin MD , Amisha Patel MD , Dasari Prasada Rao MBBS, MS, MCh , Kaushal Pandey MBBS, MCh , Isaac George MD
{"title":"发展中国家的风湿性心脏病","authors":"Michael T. Simpson MD , Mateusz Kachel MD , Robert C. Neely MD , W. Clinton Erwin MD , Aleena Yasin MD , Amisha Patel MD , Dasari Prasada Rao MBBS, MS, MCh , Kaushal Pandey MBBS, MCh , Isaac George MD","doi":"10.1016/j.shj.2023.100219","DOIUrl":null,"url":null,"abstract":"<div><p>Despite recent public policy initiatives, rheumatic heart disease (RHD) remains a major source of morbidity worldwide. Rheumatic heart disease occurs as a sequela of <em>Streptococcus pyogenes</em> (group A streptococcal [GAS]) infection in patients with genetic susceptibility. Strategies for prevention of RHD or progression of RHD include prevention of GAS infection with community initiatives, effective treatment of GAS infection, and secondary prophylaxis with intramuscular penicillin. The cardiac surgical community has attempted to improve the availability of surgery in RHD-endemic areas with some success, and operative techniques and outcomes of valve repair continue to improve, potentially offering patients a safer, more durable operation. Innovation offers hope for a more scalable solution with improved biomaterials and transcatheter delivery technology; however, cost remains a barrier.</p></div>","PeriodicalId":36053,"journal":{"name":"Structural Heart","volume":"7 6","pages":"Article 100219"},"PeriodicalIF":1.4000,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2474870623001057/pdfft?md5=ef21e1bacad86ba04cf2e936b16cd85d&pid=1-s2.0-S2474870623001057-main.pdf","citationCount":"0","resultStr":"{\"title\":\"Rheumatic Heart Disease in the Developing World\",\"authors\":\"Michael T. Simpson MD , Mateusz Kachel MD , Robert C. Neely MD , W. Clinton Erwin MD , Aleena Yasin MD , Amisha Patel MD , Dasari Prasada Rao MBBS, MS, MCh , Kaushal Pandey MBBS, MCh , Isaac George MD\",\"doi\":\"10.1016/j.shj.2023.100219\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>Despite recent public policy initiatives, rheumatic heart disease (RHD) remains a major source of morbidity worldwide. Rheumatic heart disease occurs as a sequela of <em>Streptococcus pyogenes</em> (group A streptococcal [GAS]) infection in patients with genetic susceptibility. Strategies for prevention of RHD or progression of RHD include prevention of GAS infection with community initiatives, effective treatment of GAS infection, and secondary prophylaxis with intramuscular penicillin. The cardiac surgical community has attempted to improve the availability of surgery in RHD-endemic areas with some success, and operative techniques and outcomes of valve repair continue to improve, potentially offering patients a safer, more durable operation. Innovation offers hope for a more scalable solution with improved biomaterials and transcatheter delivery technology; however, cost remains a barrier.</p></div>\",\"PeriodicalId\":36053,\"journal\":{\"name\":\"Structural Heart\",\"volume\":\"7 6\",\"pages\":\"Article 100219\"},\"PeriodicalIF\":1.4000,\"publicationDate\":\"2023-11-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.sciencedirect.com/science/article/pii/S2474870623001057/pdfft?md5=ef21e1bacad86ba04cf2e936b16cd85d&pid=1-s2.0-S2474870623001057-main.pdf\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Structural Heart\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2474870623001057\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"CARDIAC & CARDIOVASCULAR SYSTEMS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Structural Heart","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2474870623001057","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"CARDIAC & CARDIOVASCULAR SYSTEMS","Score":null,"Total":0}
Despite recent public policy initiatives, rheumatic heart disease (RHD) remains a major source of morbidity worldwide. Rheumatic heart disease occurs as a sequela of Streptococcus pyogenes (group A streptococcal [GAS]) infection in patients with genetic susceptibility. Strategies for prevention of RHD or progression of RHD include prevention of GAS infection with community initiatives, effective treatment of GAS infection, and secondary prophylaxis with intramuscular penicillin. The cardiac surgical community has attempted to improve the availability of surgery in RHD-endemic areas with some success, and operative techniques and outcomes of valve repair continue to improve, potentially offering patients a safer, more durable operation. Innovation offers hope for a more scalable solution with improved biomaterials and transcatheter delivery technology; however, cost remains a barrier.
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