七氟醚/舒芬太尼联合麻醉在小儿外科气管异物取出中的应用及其对血流动力学的影响

IF 0.6 4区 医学 Q4 PHARMACOLOGY & PHARMACY
Huaqu Gong, Tingting Liu, Lirong Duan, Lirong Duan, Haiyang Wang
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引用次数: 0

摘要

目的:探讨七氟醚+舒芬太尼联合麻醉在小儿气管异物取出术中的疗效及对血流动力学的影响。方法:将128例呼吸道异物患儿分为对照组和研究组,每组64例。对照组慢速静脉注射异丙酚(3mg /kg)。研究组患者给予5%七氟醚,缓慢静脉注射舒芬太尼(0.3 μg/kg)。血流动力学参数(舒张压、收缩压和心率)记录在麻醉诱导前、插管时、放置刚性支气管镜时(放置晶状体时)、取出异物时和拔管时。记录两组患儿气道异物取出后的并发症。结果:在插管和拔管时,两组患者血压和心率均明显升高,但研究组血压和心率明显降低。两组患儿气道异物取出术的主要并发症为呕吐、支气管痉挛和屏气。结论:七氟醚联合舒芬太尼对气管插管患儿的麻醉效果优于异丙酚,且对血流动力学的影响较小。此外,孩子们醒得更快,并发症也更少。联合麻醉安全可靠。然而,这种联合麻醉的临床应用需要更大样本的临床研究。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Combined sevoflurane/sufentanil anesthesia for removal of tracheal foreign bodies in pediatric surgery, and its effect on hemodynamics
Purpose: To determine the efficacy of sevoflurane + sufentanil combination anesthesia in pediatric surgery for removal of tracheal foreign bodies, and its effect on hemodynamics.Methods: A total of 128 children with airway foreign bodies were assigned to control and study groups, each with 64 children. The control patients received slow intravenous injection of propofol (3 mg/kg). The study group was given 5 % sevoflurane and a slow intravenous injection of sufentanil (0.3 μg/kg). Hemodynamic parameters (diastolic blood pressure, systolic blood pressure and heart rate) were recorded before induction of anesthesia, at the time of intubation, during placement of a rigid bronchoscope (when the lens was placed), during removal of foreign bodies, and when extubating. Complications in children in the two groups after the removal of airway foreign body were recorded.Results: At the times of intubation and extubation, blood pressure and heart rate were significantly increased in both groups, but appreciably lower values were seen in study group. The major complications in pediatric airway foreign body removal in two groups were vomiting, bronchospasm and holding of breath.Conclusion: In children with airway extraction, sevoflurane, in combination with sufentanil produced better anesthetic effect and less impact on hemodynamics than propofol. Moreover, the children woke up faster and had fewer complications. The combined anesthesia is safe and reliable. However, the clinical application of this combined anesthesia requires larger-sample clinical studies.
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来源期刊
CiteScore
1.00
自引率
33.30%
发文量
490
审稿时长
4-8 weeks
期刊介绍: We seek to encourage pharmaceutical and allied research of tropical and international relevance and to foster multidisciplinary research and collaboration among scientists, the pharmaceutical industry and the healthcare professionals. We publish articles in pharmaceutical sciences and related disciplines (including biotechnology, cell and molecular biology, drug utilization including adverse drug events, medical and other life sciences, and related engineering fields). Although primarily devoted to original research papers, we welcome reviews on current topics of special interest and relevance.
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