Elranatamab (Elrexfio)治疗多发性骨髓瘤

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Accounts of Chemical Research Pub Date : 2023-09-18 DOI:10.58347/tml.2023.1685d

引用次数: 0

摘要

Elranatamab-bcmm (Elrexfio -辉瑞)是一种双特异性b细胞成熟抗原(BCMA)导向的CD3 t细胞参与剂，已被FDA加速批准用于治疗复发或难治性多发性骨髓瘤，该患者先前接受过≥4种治疗，包括蛋白酶体抑制剂，免疫调节药物和抗cd38单克隆抗体。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Elranatamab (Elrexfio) for Multiple Myeloma

Elranatamab-bcmm (Elrexfio – Pfizer), a bispecific B-cell maturation antigen (BCMA)-directed CD3 T-cell engager, has been granted accelerated approval by the FDA for treatment of relapsed or refractory multiple myeloma in adults who received ≥4 prior lines of therapy, including a proteasome inhibitor, an immunomodulatory drug, and an anti-CD38 monoclonal antibody.

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.