里约热内卢州先天性梅毒的悲惨写照。用聚合酶链反应(PCR)检测皮肤病变刮屑和胎盘碎片梅毒螺旋体阳性病例报告

Felipe Dinau Leal Passos, Anderlúcia Corrêa Guedes, Ariela Gomes de Melo, Renata de Queiroz Varella, Isabelle Carvalho Rangel, Ricardo de Souza Carvalho, Fernando Raphael de Almeida Ferry, Julia Sampaio de Souza Morais, Carolina Varella Leal Passos, Paula Varella Leal Passos
{"title":"里约热内卢州先天性梅毒的悲惨写照。用聚合酶链反应(PCR)检测皮肤病变刮屑和胎盘碎片梅毒螺旋体阳性病例报告","authors":"Felipe Dinau Leal Passos, Anderlúcia Corrêa Guedes, Ariela Gomes de Melo, Renata de Queiroz Varella, Isabelle Carvalho Rangel, Ricardo de Souza Carvalho, Fernando Raphael de Almeida Ferry, Julia Sampaio de Souza Morais, Carolina Varella Leal Passos, Paula Varella Leal Passos","doi":"10.5327/dst-2177-8264-2023351382","DOIUrl":null,"url":null,"abstract":"Introduction: Congenital syphilis is a serious public health problem that causes high rates of intrauterine morbidity and mortality, revealing flaws and weaknesses in the health system. Objective: to report a case of congenital syphilis in a university hospital in the Center-South Region of the State of Rio de Janeiro, Brazil. Case report: A pregnant woman, aged between 19 and 23 years old, carrying a Pregnant Woman’s Handbook with a record of seven prenatal consultations and a note of the serological reaction for positive syphilis, but without any treatment, hospitalized at the University Hospital of Vassouras (RJ), in labor, gave birth to a newborn (NB) with a clinical picture and serological test of congenital syphilis. The NB required care in an intensive care unit and was discharged 28 days after birth. Scraping of skin lesions of the NB and placenta was performed for analysis by molecular biology (PCR in house) and genetic material of Treponema pallidum was detected. Conclusion: Congenital syphilis is a serious outcome of syphilis during pregnancy, consuming high financial resources and significant emotional distress for the mother, father, the whole family, as well as for the health teams. Our case report was the first that we are aware of in Brazil with a diagnosis by PCR for positive Treponema pallidum of skin scraping and placental fragment. It also showed poor quality prenatal care, a common factor in most cases of CS in our reality.","PeriodicalId":472873,"journal":{"name":"DST","volume":"153 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"A sad portrait of congenital syphilis in the State of Rio de Janeiro. Case report with Polymerase Chain Reaction (PCR) of scrapings from skin lesions and placenta fragment positive for Treponema pallidum\",\"authors\":\"Felipe Dinau Leal Passos, Anderlúcia Corrêa Guedes, Ariela Gomes de Melo, Renata de Queiroz Varella, Isabelle Carvalho Rangel, Ricardo de Souza Carvalho, Fernando Raphael de Almeida Ferry, Julia Sampaio de Souza Morais, Carolina Varella Leal Passos, Paula Varella Leal Passos\",\"doi\":\"10.5327/dst-2177-8264-2023351382\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Introduction: Congenital syphilis is a serious public health problem that causes high rates of intrauterine morbidity and mortality, revealing flaws and weaknesses in the health system. Objective: to report a case of congenital syphilis in a university hospital in the Center-South Region of the State of Rio de Janeiro, Brazil. Case report: A pregnant woman, aged between 19 and 23 years old, carrying a Pregnant Woman’s Handbook with a record of seven prenatal consultations and a note of the serological reaction for positive syphilis, but without any treatment, hospitalized at the University Hospital of Vassouras (RJ), in labor, gave birth to a newborn (NB) with a clinical picture and serological test of congenital syphilis. The NB required care in an intensive care unit and was discharged 28 days after birth. Scraping of skin lesions of the NB and placenta was performed for analysis by molecular biology (PCR in house) and genetic material of Treponema pallidum was detected. Conclusion: Congenital syphilis is a serious outcome of syphilis during pregnancy, consuming high financial resources and significant emotional distress for the mother, father, the whole family, as well as for the health teams. Our case report was the first that we are aware of in Brazil with a diagnosis by PCR for positive Treponema pallidum of skin scraping and placental fragment. It also showed poor quality prenatal care, a common factor in most cases of CS in our reality.\",\"PeriodicalId\":472873,\"journal\":{\"name\":\"DST\",\"volume\":\"153 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"DST\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.5327/dst-2177-8264-2023351382\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"DST","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.5327/dst-2177-8264-2023351382","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

摘要

先天性梅毒是一个严重的公共卫生问题,导致宫内发病率和死亡率高,暴露了卫生系统的缺陷和弱点。目的:报告巴西里约热内卢州中南部地区某大学医院一例先天性梅毒病例。病例报告:一名年龄在19至23岁之间的孕妇,携带一本孕妇手册,记录了七次产前咨询和梅毒阳性血清学反应,但未经任何治疗,在瓦苏拉斯大学医院(RJ)住院,分娩时生下了一名新生儿(NB),患有先天性梅毒的临床图片和血清学检查。新生儿需要在重症监护病房进行护理,并在出生后28天出院。刮痧新生儿和胎盘皮损处进行分子生物学分析(室内PCR),检测梅毒螺旋体遗传物质。结论:先天性梅毒是妊娠期梅毒的一种严重后果,对母亲、父亲、整个家庭以及卫生团队都消耗了大量的经济资源和巨大的精神压力。我们的病例报告是我们在巴西所知的第一个通过PCR诊断为皮肤刮擦和胎盘碎片阳性梅毒螺旋体的病例。这也表明产前护理质量差,这是我们现实中大多数CS病例的共同因素。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A sad portrait of congenital syphilis in the State of Rio de Janeiro. Case report with Polymerase Chain Reaction (PCR) of scrapings from skin lesions and placenta fragment positive for Treponema pallidum
Introduction: Congenital syphilis is a serious public health problem that causes high rates of intrauterine morbidity and mortality, revealing flaws and weaknesses in the health system. Objective: to report a case of congenital syphilis in a university hospital in the Center-South Region of the State of Rio de Janeiro, Brazil. Case report: A pregnant woman, aged between 19 and 23 years old, carrying a Pregnant Woman’s Handbook with a record of seven prenatal consultations and a note of the serological reaction for positive syphilis, but without any treatment, hospitalized at the University Hospital of Vassouras (RJ), in labor, gave birth to a newborn (NB) with a clinical picture and serological test of congenital syphilis. The NB required care in an intensive care unit and was discharged 28 days after birth. Scraping of skin lesions of the NB and placenta was performed for analysis by molecular biology (PCR in house) and genetic material of Treponema pallidum was detected. Conclusion: Congenital syphilis is a serious outcome of syphilis during pregnancy, consuming high financial resources and significant emotional distress for the mother, father, the whole family, as well as for the health teams. Our case report was the first that we are aware of in Brazil with a diagnosis by PCR for positive Treponema pallidum of skin scraping and placental fragment. It also showed poor quality prenatal care, a common factor in most cases of CS in our reality.
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
DST
DST
自引率
0.00%
发文量
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信