小细胞乳腺癌。病例报告

P. Leszczyńska, M. Sobocińska, K. Ustymowicz, W. Romańczyk
{"title":"小细胞乳腺癌。病例报告","authors":"P. Leszczyńska, M. Sobocińska, K. Ustymowicz, W. Romańczyk","doi":"10.5604/01.3001.0053.7466","DOIUrl":null,"url":null,"abstract":"Introduction: Primary small cell breast carcinomais a highly malignant, uncommon cancer, whichaccounts for less than 1% of all breast cancers. It isusually found in women over 60 years of age as apalpable tumour of the breast or armpit. Due to thesmall number of relevant case reports, this type ofcancer presents a diagnostic and therapeuticchallenge.Case presentation: A 85-year-old woman showedup at the Oncology Clinic with a palpable node in theleft breast. On physical examination, the patient wasin general good condition, ECOG performancestatus of 1. In deviations from the norm, there was apalpable tumour with a diameter of ca. 4cm in thelower outer quadrant, 4 o'clock position of the leftbreast; and an enlarged, movable left axillary lymphnode, with a diameter of about 3 cm. The diagnosis,strongly influenced by the abovementioned tests,was small cell breast cancer TNBC-cT2N1M0. Asagreed at the case conference meeting, the patientwas qualified for neoadjuvant chemotherapyaccording to the 4-EP scheme, followed bymastectomy with lymphadenectomy of the leftarmpit and complementary radiotherapy. The patientreceived four courses of chemotherapy from 28March to 30 May 2023. The visible tumourregression in physical examination revealed goodtreatment tolerance – a reduction of tumour size onpalpation by half. The patient is undergoing followup checks after chemotherapy and awaits ascheduled surgery.Conclusions: Literature on primary small cell breastcarcinoma is still limited . Diagnostics of SCNCBinclude positron emission tomography (PET) and CTscans to rule out metastases from another primarylocation. Clinical treatment of SCNCB is stillunderdeveloped. A particularly important prognosticfactor is the size of tumour at the time of treatment.Early detection and interdisciplinary therapies maybe relevant for improving prognosis. Research on thediagnosis, treatment and prognosis of SCNCB is stillongoing.","PeriodicalId":138155,"journal":{"name":"Progress in Health Sciences","volume":"253 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Small cell breast carcinoma. Case report\",\"authors\":\"P. Leszczyńska, M. Sobocińska, K. Ustymowicz, W. Romańczyk\",\"doi\":\"10.5604/01.3001.0053.7466\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Introduction: Primary small cell breast carcinomais a highly malignant, uncommon cancer, whichaccounts for less than 1% of all breast cancers. It isusually found in women over 60 years of age as apalpable tumour of the breast or armpit. Due to thesmall number of relevant case reports, this type ofcancer presents a diagnostic and therapeuticchallenge.Case presentation: A 85-year-old woman showedup at the Oncology Clinic with a palpable node in theleft breast. On physical examination, the patient wasin general good condition, ECOG performancestatus of 1. In deviations from the norm, there was apalpable tumour with a diameter of ca. 4cm in thelower outer quadrant, 4 o'clock position of the leftbreast; and an enlarged, movable left axillary lymphnode, with a diameter of about 3 cm. The diagnosis,strongly influenced by the abovementioned tests,was small cell breast cancer TNBC-cT2N1M0. Asagreed at the case conference meeting, the patientwas qualified for neoadjuvant chemotherapyaccording to the 4-EP scheme, followed bymastectomy with lymphadenectomy of the leftarmpit and complementary radiotherapy. The patientreceived four courses of chemotherapy from 28March to 30 May 2023. The visible tumourregression in physical examination revealed goodtreatment tolerance – a reduction of tumour size onpalpation by half. The patient is undergoing followup checks after chemotherapy and awaits ascheduled surgery.Conclusions: Literature on primary small cell breastcarcinoma is still limited . Diagnostics of SCNCBinclude positron emission tomography (PET) and CTscans to rule out metastases from another primarylocation. Clinical treatment of SCNCB is stillunderdeveloped. A particularly important prognosticfactor is the size of tumour at the time of treatment.Early detection and interdisciplinary therapies maybe relevant for improving prognosis. Research on thediagnosis, treatment and prognosis of SCNCB is stillongoing.\",\"PeriodicalId\":138155,\"journal\":{\"name\":\"Progress in Health Sciences\",\"volume\":\"253 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-06-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Progress in Health Sciences\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.5604/01.3001.0053.7466\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Progress in Health Sciences","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.5604/01.3001.0053.7466","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

摘要

原发性小细胞乳腺癌是一种高度恶性的罕见癌症,占所有乳腺癌的不到1%。它通常在60岁以上的女性身上发现,表现为乳房或腋窝的明显肿瘤。由于相关病例报告较少,这种类型的癌症提出了诊断和治疗的挑战。病例介绍:一名85岁的女性因左乳房可触及的淋巴结出现在肿瘤诊所。体格检查,患者总体状况良好,ECOG表现为1。偏离正常值,左乳4点钟位置外下象限可见直径约4cm的肿瘤;左侧腋窝淋巴结肿大,可活动,直径约3cm。在上述检查的强烈影响下,诊断结果为小细胞乳腺癌TNBC-cT2N1M0。经病例会议一致同意,患者符合4-EP方案,行新辅助化疗,左腋窝淋巴结切除,辅助放疗。患者于2023年3月28日至5月30日接受了4个疗程的化疗。体格检查中可见的肿瘤消退显示出良好的治疗耐受性-触诊时肿瘤大小减少了一半。患者正在接受化疗后的随访检查,并等待预定的手术。结论:关于原发性小细胞乳腺癌的文献仍然有限。scncb的诊断包括正电子发射断层扫描(PET)和ct扫描,以排除其他原发部位的转移。SCNCB的临床治疗仍不发达。一个特别重要的预后因素是治疗时肿瘤的大小。早期发现和综合治疗可能有助于改善预后。对SCNCB的诊断、治疗及预后的研究仍在进行中。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Small cell breast carcinoma. Case report
Introduction: Primary small cell breast carcinomais a highly malignant, uncommon cancer, whichaccounts for less than 1% of all breast cancers. It isusually found in women over 60 years of age as apalpable tumour of the breast or armpit. Due to thesmall number of relevant case reports, this type ofcancer presents a diagnostic and therapeuticchallenge.Case presentation: A 85-year-old woman showedup at the Oncology Clinic with a palpable node in theleft breast. On physical examination, the patient wasin general good condition, ECOG performancestatus of 1. In deviations from the norm, there was apalpable tumour with a diameter of ca. 4cm in thelower outer quadrant, 4 o'clock position of the leftbreast; and an enlarged, movable left axillary lymphnode, with a diameter of about 3 cm. The diagnosis,strongly influenced by the abovementioned tests,was small cell breast cancer TNBC-cT2N1M0. Asagreed at the case conference meeting, the patientwas qualified for neoadjuvant chemotherapyaccording to the 4-EP scheme, followed bymastectomy with lymphadenectomy of the leftarmpit and complementary radiotherapy. The patientreceived four courses of chemotherapy from 28March to 30 May 2023. The visible tumourregression in physical examination revealed goodtreatment tolerance – a reduction of tumour size onpalpation by half. The patient is undergoing followup checks after chemotherapy and awaits ascheduled surgery.Conclusions: Literature on primary small cell breastcarcinoma is still limited . Diagnostics of SCNCBinclude positron emission tomography (PET) and CTscans to rule out metastases from another primarylocation. Clinical treatment of SCNCB is stillunderdeveloped. A particularly important prognosticfactor is the size of tumour at the time of treatment.Early detection and interdisciplinary therapies maybe relevant for improving prognosis. Research on thediagnosis, treatment and prognosis of SCNCB is stillongoing.
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
自引率
0.00%
发文量
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信