电子烟使用者健康影响预测

I. L. Vysochyna, T. O. Yashkina
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引用次数: 0

摘要

电子烟在烟草市场上迅速流行起来,主要是在年轻人中。商家利用缺乏证据证明它们对健康的影响,把它们标榜为传统香烟的安全替代品。我们的研究旨在扩大现有的证据,证明它们对人体的影响。目的:通过对临床和实验室检查数据的统计分析,找出电子烟使用者最显著的特征。材料与方法。该研究包括102名参与者(主要组- 66名使用电子烟作为替代吸烟方式的个人;对照组——36名不使用电子烟或工业香烟的人,年龄在20至35岁之间。每位参与者都提供了参与的书面知情同意书。患者检查包括以下参数:身高、体重、体质指数(BMI)计算;测量血压、心率、脉搏和呼吸频率;收集咽拭子。结果。根据我们的数据,主组的个体有更高的身高、体重和BMI值。较高的BMI可能与唾液腺的过度刺激有关,从而导致胃液分泌增加和食欲刺激。与对照组相比,电子烟使用者的血压水平明显更高。咽拭子中尼古丁传递系统的使用者有明显更高水平的粘液、球菌菌群和中性粒细胞百分比,表明口腔粘膜中存在细菌制剂。这可能与细菌通过尼古丁输送装置传播有关。我们对潜在的患者特征进行了多重逻辑回归分析。结论。与不吸烟的同龄人相比,电子烟使用者的特点是身高、体重、身体质量指数、血压水平更高,适应潜力降低,副交感神经系统调节普遍存在。结果发现,典型的电子烟使用者为男性(OR = 15.9364),功能能力的IFZ -适应电位降低(OR = 7.8128),口腔菌群数量异常(OR = 1.7748)。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Health implications forecast for electronic cigarette users
Electronic cigarettes have rapidly gained popularity in the tobacco market, primarily among young adults. Marketers exploit the lack of evidence regarding their health effects and label them as a safe alternative to traditional cigarettes. Our study aims to expand the existing body of evidence on their impact on the human body. Objective: To identify the most significant characteristics of individuals using electronic cigarettes based on statistical analysis of clinical and laboratory examination data. Materials and Methods. The study included 102 participants (main group – 66 individuals using electronic cigarettes as an alternative form of smoking; control group – 36 individuals who did not use electronic or industrial cigarettes) aged 20 to 35 years. Each participant provided written informed consent to participate. Patient examinations included the following parameters: height, weight, body mass index (BMI) calculation; measurement of blood pressure, heart rate, pulse, and respiratory rate; throat swab collection. Results. According to our data, individuals in the main group had higher height, weight, and BMI values. A higher BMI may be associated with excessive stimulation of salivary glands and, consequently, increased gastric secretion and appetite stimulation. Electronic cigarette users had significantly higher blood pressure levels compared to the control group. Users of nicotine delivery systems in throat swabs had significantly higher levels of mucus, coccal flora, and neutrophil percentage, indicating the presence of bacterial agents in the oral cavity mucosa. This may be related to bacterial agents’ dissemination through nicotine delivery devices. We conducted multiple logistic regression analysis with potential patient characteristics. Conclusions. Electronic cigarette users are characterized by higher height, weight, BMI, blood pressure levels compared to non-smoking peers, as well as reduced adaptation potential and a prevalence of parasympathetic nervous system regulation. It was found that a typical electronic cigarette user is a male (OR = 15.9364) with reduced IFZ – adaptive potential of functional abilities (OR = 7.8128) and an abnormal amount of oral cavity flora (OR = 1.7748).
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