1例青壮年急性髓系白血病及文献回顾

IF 0.6 Q4 ONCOLOGY

Case Reports in Oncological Medicine Pub Date : 2023-11-11 DOI:10.1155/2023/6628492

Carlee Blakemore, Sudarshawn Damodharan, Diane Puccetti

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引用次数: 0

摘要

具有高风险变异inv(3)/t(3;3)或t(3;3)(q21;26.2)的急性髓性白血病(AML)在儿科和青年人群中罕见。它与治疗方案无效的不良结果有关。在这里，我们提出了一例18岁的女性治疗难治性inv(3) AML，无法获得缓解。鉴于该亚型所描述的对传统疗法的耐药性增加，需要更好的治疗方案。在这里，我们回顾了儿科和青少年AML的文献以及新的治疗方案。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Inv(3) Acute Myeloid Leukemia in a Young Adult and Review of the Literature

Acute myeloid leukemia (AML) with the high-risk variant inv(3)/t(3;3) or t(3;3)(q21;26.2) is rarely seen in the pediatric and young adult population. It is associated with poor outcomes with ineffective therapeutic options. Here, we present a case of an 18-year-old female with treatment refractory inv(3) AML in whom remission was unable to be obtained. Better treatment options are needed given the increased resistance to traditional therapy this subtype portrays. Here, we review the literature on pediatric and young adult inv(3) AML along with newer therapeutic options.

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来源期刊

Case Reports in Oncological Medicine ONCOLOGY-

自引率

0.00%

发文量

审稿时长

16 weeks

期刊介绍： Case Reports in Oncological Medicine is a peer-reviewed, Open Access journal that publishes case reports and case series related to breast cancer, lung cancer, gastrointestinal cancer, skin cancer, head and neck cancer, paediatric oncology, neurooncology as well as genitourinary cancer.