Knowledge, attitude and the acceptance of using covid-19 vaccine among High school students at Nam Dinh province in 2021

Background: This cross-sectional study among 404 students at Quat Lam High School, Nam Dinh province was conducted to describe the current status of their knowledge, attitude, acceptance of using the COVID-19 vaccine, and related factors. Results 86.9% of students know that the COVID-19 vaccine has a protective effect of more than 50%. 90.1% of students know that receiving a full dose of COVID-19 vaccine does not provide them lifelong protection.; Students have a positive attitude toward vaccination: 82.6% of students agree that getting the full basic dose of COVID-19 vaccine would reduce the number of COVID-19 cases; 85.9% of the students think that a basic dose of COVID-19 vaccine would reduce complication and mortality rate Among 98.7% of vaccinated students, 69.8% of them accepted the vaccination. Whereas factors such as gender, grade, and the potential of infecting COVID-19 have no statistically significant association with vaccination acceptance, family support did with OR = 7.75 (95% CI 1.41-37.05, P=0.0054). Conclusion: The results suggest that enhancing communication through student's families is necessary to increase the acceptance of vaccination among students. Keywords: COVID-19 vaccine, knowledge, attitude, acceptance, high school students