{"title":"临床实践中未公开的安慰剂试验:秘密的善行还是无端的欺骗?","authors":"Daniel Edward Callies","doi":"10.1353/nib.2023.0017","DOIUrl":null,"url":null,"abstract":"A placebo is an intervention that is believed to lack specific pharmacological or physiological efficacy for a patient's condition. While placebo-controlled trials are considered the gold standard when it comes to researching and testing new pharmacological treatments, the use of placebos in clinical practice is more controversial. The focus of this case study is an undisclosed placebo trial used as an attempt to diagnose a patient's complex and unusual symptomology. In this case, the placebo was used not just as a treatment, but as a diagnostic intervention in order to determine the best course of treatment for a patient. Could the deceptive use of a placebo be justified in clinical practice on the grounds of beneficence?","PeriodicalId":37978,"journal":{"name":"Narrative inquiry in bioethics","volume":"10 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Undisclosed Placebo Trials in Clinical Practice: Undercover Beneficence or Unwarranted Deception?\",\"authors\":\"Daniel Edward Callies\",\"doi\":\"10.1353/nib.2023.0017\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"A placebo is an intervention that is believed to lack specific pharmacological or physiological efficacy for a patient's condition. While placebo-controlled trials are considered the gold standard when it comes to researching and testing new pharmacological treatments, the use of placebos in clinical practice is more controversial. The focus of this case study is an undisclosed placebo trial used as an attempt to diagnose a patient's complex and unusual symptomology. In this case, the placebo was used not just as a treatment, but as a diagnostic intervention in order to determine the best course of treatment for a patient. Could the deceptive use of a placebo be justified in clinical practice on the grounds of beneficence?\",\"PeriodicalId\":37978,\"journal\":{\"name\":\"Narrative inquiry in bioethics\",\"volume\":\"10 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-03-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Narrative inquiry in bioethics\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1353/nib.2023.0017\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Narrative inquiry in bioethics","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1353/nib.2023.0017","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Medicine","Score":null,"Total":0}
Undisclosed Placebo Trials in Clinical Practice: Undercover Beneficence or Unwarranted Deception?
A placebo is an intervention that is believed to lack specific pharmacological or physiological efficacy for a patient's condition. While placebo-controlled trials are considered the gold standard when it comes to researching and testing new pharmacological treatments, the use of placebos in clinical practice is more controversial. The focus of this case study is an undisclosed placebo trial used as an attempt to diagnose a patient's complex and unusual symptomology. In this case, the placebo was used not just as a treatment, but as a diagnostic intervention in order to determine the best course of treatment for a patient. Could the deceptive use of a placebo be justified in clinical practice on the grounds of beneficence?
期刊介绍:
Narrative Inquiry in Bioethics (NIB) is a unique journal that provides a forum for exploring current issues in bioethics through personal stories, qualitative and mixed-methods research articles, and case studies. NIB is dedicated to fostering a deeper understanding of bioethical issues by publishing rich descriptions of complex human experiences written in the words of the person experiencing them. While NIB upholds appropriate standards for narrative inquiry and qualitative research, it seeks to publish articles that will appeal to a broad readership of healthcare providers and researchers, bioethicists, sociologists, policy makers, and others. Articles may address the experiences of patients, family members, and health care workers.