{"title":"支气管哮喘患者的跨学科监测","authors":"Corina Eugenia Budin, Gabriela-Paula Pop","doi":"10.26416/med.154.4.2023.8709","DOIUrl":null,"url":null,"abstract":"Bronchial asthma is characterized by chronic inflammation of the airways, associated with variable obstruction that limits air flow, and bronchial hyperactivity caused by various stimuli. The most common symptoms present in asthmatic people are wheezing, dyspnea, cough and chest constriction. Bronchial asthma has a high variability, which makes its phenotyping very important for guiding treatment. Among the most common phenotypes, we mention allergic asthma, nonallergic asthma, late-onset bronchial asthma, persistent asthma with a fixed limitation of airflow, and asthma associated with obesity. A thorough anamnesis and performing spirometry with bronchodilator test help us to establish the diagnosis of bronchial asthma. The increase in the maximum expiratory volume per second (VEMS) by 12% and 200 ml from the initial value after taking four short-acting bronchodilator puffs is suggestive of bronchial asthma. The ACT questionnaire is used to show whether the disease is well controlled therapeutically. Exposure to allergens, overweight, gastroesophageal reflux disease, rhinosinusitis, nasal polyposis and smoking are some of the comorbidities and triggers of bronchial asthma crisis. In terms of treatment, asthmatic patients have inhaled devices that contain as the first line of treatment inhaled corticosteroids to which a long-acting beta2-agonist is added. Choosing the right therapy for each patient is made on the basis of five stages of treatment, depending on the symptomatology of each individual patient, the phenotype of asthma and the comorbidities present. Patients with severe asthma benefit from targeted biological therapy.","PeriodicalId":489459,"journal":{"name":"Medic.ro","volume":"4 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Interdisciplinary monitoring of the patient with bronchial asthma\",\"authors\":\"Corina Eugenia Budin, Gabriela-Paula Pop\",\"doi\":\"10.26416/med.154.4.2023.8709\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Bronchial asthma is characterized by chronic inflammation of the airways, associated with variable obstruction that limits air flow, and bronchial hyperactivity caused by various stimuli. The most common symptoms present in asthmatic people are wheezing, dyspnea, cough and chest constriction. Bronchial asthma has a high variability, which makes its phenotyping very important for guiding treatment. Among the most common phenotypes, we mention allergic asthma, nonallergic asthma, late-onset bronchial asthma, persistent asthma with a fixed limitation of airflow, and asthma associated with obesity. A thorough anamnesis and performing spirometry with bronchodilator test help us to establish the diagnosis of bronchial asthma. The increase in the maximum expiratory volume per second (VEMS) by 12% and 200 ml from the initial value after taking four short-acting bronchodilator puffs is suggestive of bronchial asthma. The ACT questionnaire is used to show whether the disease is well controlled therapeutically. Exposure to allergens, overweight, gastroesophageal reflux disease, rhinosinusitis, nasal polyposis and smoking are some of the comorbidities and triggers of bronchial asthma crisis. In terms of treatment, asthmatic patients have inhaled devices that contain as the first line of treatment inhaled corticosteroids to which a long-acting beta2-agonist is added. Choosing the right therapy for each patient is made on the basis of five stages of treatment, depending on the symptomatology of each individual patient, the phenotype of asthma and the comorbidities present. Patients with severe asthma benefit from targeted biological therapy.\",\"PeriodicalId\":489459,\"journal\":{\"name\":\"Medic.ro\",\"volume\":\"4 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Medic.ro\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.26416/med.154.4.2023.8709\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Medic.ro","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.26416/med.154.4.2023.8709","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
摘要
支气管哮喘的特征是气道的慢性炎症,伴有限制空气流动的变异性阻塞,以及由各种刺激引起的支气管过度活跃。哮喘患者最常见的症状是喘息、呼吸困难、咳嗽和胸闷。支气管哮喘具有很高的变异性,这使得其表型对指导治疗非常重要。在最常见的表型中,我们提到过敏性哮喘、非过敏性哮喘、迟发性支气管哮喘、固定气流受限的持续性哮喘以及与肥胖相关的哮喘。彻底的记忆和支气管扩张试验的肺活量测定有助于我们确定支气管哮喘的诊断。服用四次短效支气管扩张剂后,最大每秒呼气量(VEMS)比初始值增加12%和200ml,提示支气管哮喘。ACT问卷用于显示疾病在治疗上是否得到良好控制。暴露于过敏原、超重、胃食管反流病、鼻窦炎、鼻腔息肉病和吸烟是支气管哮喘危象的一些合并症和诱发因素。在治疗方面,哮喘患者的吸入装置含有作为一线治疗的吸入co - ti - co - ste - roids,其中添加了长效β - 2激动剂。为每位患者选择合适的治疗方案是基于五个治疗阶段,这取决于每位患者的症状-病症-病症、哮喘的表型和存在的共病-病症。严重哮喘患者受益于靶向生物治疗。
Interdisciplinary monitoring of the patient with bronchial asthma
Bronchial asthma is characterized by chronic inflammation of the airways, associated with variable obstruction that limits air flow, and bronchial hyperactivity caused by various stimuli. The most common symptoms present in asthmatic people are wheezing, dyspnea, cough and chest constriction. Bronchial asthma has a high variability, which makes its phenotyping very important for guiding treatment. Among the most common phenotypes, we mention allergic asthma, nonallergic asthma, late-onset bronchial asthma, persistent asthma with a fixed limitation of airflow, and asthma associated with obesity. A thorough anamnesis and performing spirometry with bronchodilator test help us to establish the diagnosis of bronchial asthma. The increase in the maximum expiratory volume per second (VEMS) by 12% and 200 ml from the initial value after taking four short-acting bronchodilator puffs is suggestive of bronchial asthma. The ACT questionnaire is used to show whether the disease is well controlled therapeutically. Exposure to allergens, overweight, gastroesophageal reflux disease, rhinosinusitis, nasal polyposis and smoking are some of the comorbidities and triggers of bronchial asthma crisis. In terms of treatment, asthmatic patients have inhaled devices that contain as the first line of treatment inhaled corticosteroids to which a long-acting beta2-agonist is added. Choosing the right therapy for each patient is made on the basis of five stages of treatment, depending on the symptomatology of each individual patient, the phenotype of asthma and the comorbidities present. Patients with severe asthma benefit from targeted biological therapy.