Platelet Rich Fibrinin the management of Perio-Endo Lesion –A Case report

The tooth, the pulp tissue within it and its supporting structures should be viewed as one biological unit. The interrelationship of these structures influences each other during health, function, and disease. the periodontium and pulp have embryonic, anatomic and functional interrelationship. Dental papilla and follicle form embryologically from ectomesenchymal cell proliferation, and they are the precursors of the periodontium and the pulp respectively and they give rise to anatomical connections, which remain throughout life. As the root develops, ectomesenchymal channels get incorporated, either due to dentine formation around existing blood vessels or breaks in the continuity of the Hertwig epithelial root sheath, to become accessory or lateral canals. The majority of accessory canals and lateral canals are found in the apical part of the root and molar furcation regions respectively. The exposure of dentinal tubules to the periodontium due to the absence of overlying cementum creates communication between pulp and periodontium. The pathological agents pass between the periodontium and pulp through these pathways, thereby creating the perio-endo lesion. 4