A Review on Antimicrobial Activity of Tarunyapidikahara Lepa Ingredients

Skin is not only a protecting covering of our whole body but also it reflects the physical and mental health. Mukhdushika is the most common skin ailment in the teenage of youngsters, it disfigure the face. Acne vulgaris is chronic inflammatory condition of the pilosebacous follicles and caused by the Propionibacteriun acnes. It is correlated with Mukhdushika, a disease mention in Ayurveda. Microbial infections are the leading cause of diseases and disease related mortality. Non–judicious intake of antibiotic is the serious concern for antibiotic resistant strain of bacteria. Antimicrobial resistance (AMR) threatens the ability to successfully treat infectious diseases across the world. Among the most common skin pathogens Pseudomonas aeruginosa (gram-negative pathogen) has high antibiotic resistance rate and Staphylococcus aureus is another most common human pathogens that leads to many types of local infections such as wound, post-operative infection and also for prosthetic infections. S. aureus is also known for its ability to resist antibiotics such as penicillin, methicillin, tetracycline, erythromycin and vancomycin, so there is a need of different treatment to overcome the problem of AMR. Similar problem is also arises in the treatment of acne by antibiotics. Tarunyapidikahara Lepa is an Ayurvedic formulation consisting of equal amount of Lodhra (Symplocos racemosa Roxb), Dhanakya (Coriandrum sativum Linn.) and Vacha (Acorus calamus Linn) prescribed for topical application in Mukhdusika in renowned text Chakradatta, Kshudra Roga Chikitsa. This appraisal summarizes the antimicrobial potential of each ingredient present in the Tarunyapidikhara Lepa.