一名两岁半女童非特异性表现的 B 细胞淋巴瘤--病例报告

Ewa Krasuska-Sławińska, Izabela Królik-Elgas, Marzena Stypińska, Anna Matosek-Rutkowska
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引用次数: 0

摘要

b细胞淋巴母细胞淋巴瘤是一种非霍奇金淋巴瘤,在儿童中相当罕见。在非霍奇金淋巴瘤的过程中,骨的局灶性改变大多是继发性的改变,它们在骨的原发位置是罕见的。原发性骨淋巴瘤(PBL)主要累及股骨和胫骨;在颌骨的主要位置是零星的。在诊断方面,主要有磁共振、医学扫描(断层扫描),最重要的是组织病理学检查。也有化疗的选择,主要位置在颌骨或下颌骨显著提高预后。这项工作的目的是介绍一位从早期b细胞确诊为b细胞淋巴母细胞淋巴瘤的患者。女童曾到儿童纪念健康研究所喉科门诊、儿童口腔外科门诊、肿瘤门诊就诊。就诊的原因是右侧鼻基隆起,存在两个月,被医生误诊为该区域的创伤后肿胀。在引入实验室和扫描诊断并从病变处取活检后,得出了最终结论。同时,还介绍了b细胞淋巴母细胞淋巴瘤的治疗方案。如本病例所述,非特异性b细胞淋巴瘤的图像,特别是由于其位于颌骨且生长缓慢,可能构成巨大的诊断问题并恶化预后。因此,重要的是要考虑淋巴瘤-在病变的这种位置。此外,值得记住的是,最终的诊断可能只能通过组织病理学检查的基础上。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Niespecyficzny obraz chłoniaka B-komórkowego u dwuipółletniej dziewczynki – opis przypadku
B-cell lymphoblastic lymphoma which is a type of non-Hodgkin lymphoma is rather uncommon in children. Focal changes in bones in the course of non-Hodgkin lymphoma are mostly secondary changes and their primal location in a bone is rare. PBL (primary bone lymphoma) mainly concerns a thighbone and a tibial bone; the primary location in jaw bones is quite sporadic. In diagnostics, there is mainly magnetic resonance, medical scan (tomography), and above all – histopathological test. There is also chemotherapy by choice, and primary location in a jaw or a mandible significantly advances the prognosis. The aim of the work is to introduce a patient who was definitively diagnosed B-cell lymphoblastic lymphoma from the early B-cells. The girl reported to Laryngological Clinic, Dental Surgery Clinic for Children, Oncological Clinic of Children’s Memorial Health Institute. The cause of the visit was an elevation on the right side of a nose base, present for two months and misdiagnosed by doctors as a post-traumatic swelling in this region. After introducing laboratory and scan diagnostics and taking biopsy from the lesion, a final conclusion was made. Also, a proper treatment according to the protocol for B-cell lymphoblastic lymphoma was introduced. Non-specific B-cell lymphoma picture, as mentioned in the described case, specifically due to location in a jaw bone and a slow pace of growing, may both constitute huge diagnostic problems and deteriorate prognosis. Therefore, it is important to take into account also lymphoma – in such location of a lesion. Moreover, it is worth remembering that the final diagnosis may only be passed on the basis of histopathological examination.
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