动物衣原体病存在的问题及解决方法(综述)

Oleksandr Bindiug, V. Rokotianska
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摘要

对解决猪衣原体问题的科学趋势进行了室内分析,重点探讨了最有效的动物疾病预防和治疗方法。已经确定,衣原体被定位为细菌和病毒,因此在农场动物和家禽中相当普遍:世界上登记的动物,特别是猪中约有9000万例衣原体病新病例。某些类型的衣原体威胁着人类和动物的健康,降低了后者的生产力。衣原体是革兰氏阴性的专性胞内细菌,具有复杂的发育周期,包括两个阶段,如初级体(感染性)和网状体。这决定了它们的潜伏期和对抗生素和其他治疗药物的耐药性。已经确定衣原体与病毒相似,并且能够在动物体内引起危险的形成。猪的衣原体病表现为结膜炎、肺炎和假膜性或坏死性肠炎,这在使用临床分离物在非生物猪中进行感染的实验繁殖中得到证实。此外,衣原体与仔猪心包炎、多关节炎和多浆液炎以及许多生殖问题有关,如母猪阴道分泌物、性周期中断、流产、胎儿木乃伊化、出生仔猪虚弱、围产期和新生儿死亡率增加,以及公猪的睾丸炎、附睾炎和尿道炎。然而,对于这些疾病中的大多数,衣原体的最终作用尚未完全确定。衣原体被认为是猪的一种病原体,在大多数现有的兽医诊断实验室中不进行衣原体检测。衣原体经常与其他病原体一起发生,这种现象在一定程度上使猪的康复复杂化。动物衣原体感染是由于其粘膜与疾病病原体直接接触而发生的。系统地控制种畜中衣原体的存在将防止其生产力下降,即防止重大的经济损失。利用分子遗传方法(PCR)对衣原体进行研究,可以对病畜进行鉴定和光照,是最有前途的方法,可以保证病畜的检测。关键词:衣原体,感染,细菌,动物,猪,发病机制,症状,诊断方法
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Problems of chlamidiosis in animals and ways to solve them (review)
It was conducted a chamber analysis of scientific trends in solving the problems of chlamydia in pigs and focusing on the most effective methods of the disease prevention and the treatment of animals. It has been determined that chlamydia are positioned as bacteria and viruses, and therefore are quite common among farm animals, and poultry: about 90 million new cases of chlamydia disease in animals, in particular pigs, are registered in the world. Some types of chlamydia threaten the health of people and animals, reducing the productivity of the latter. Chlamydiae are Gram-negative, obligate intracellular bacteria with a complex developmental cycle consisting of two stages, such as the elementary body (infectious) and the reticulum body. This determines their latency and resistance to antibiotics and other therapeutic drugs. It has been determined that chlamydia are similar to viruses and have the ability to cause dangerous formations in the body of animals. Chlamydial disease in pigs manifests as conjunctivitis, pneumonia, and pseudomembranous or necrotizing enteritis, which is confirmed by the experimental reproduction of the infection in gnotobiotic pigs using clinical isolates. In addition, chlamydia is associated with pericarditis, polyarthritis and polyserositis in piglets and numerous reproductive problems such as vaginal discharge from the sow, disruption of the sexual cycle, abortions, mummification of fetuses, the birth of weak piglets, the increased perinatal and neonatal mortality, as well as orchitis, epididymitis and urethritis in boars. However, for most of these diseases, the ultimate role of chlamydia is not fully defined. Chlamydia is considered a pathogen in pigs, chlamydia tests are not performed in most available veterinary diagnostic laboratories. Chlamydia often occurs together with other pathogens, and this phenomenon complicates the recovery of pigs to a certain extent. Infection of animals with chlamydia occurs as a result of direct contact of their mucous membranes with the causative agent of the disease. The systematic control of the presence of chlamydia in animals of the breeding herd will prevent a decrease in their productivity, that is, the substantial economic losses. The study of chlamydia by the molecular genetic method (PCR) will allow to identify sick animals and carry out their illumination, which is the most promising and will ensure the detection of sick animals. Key words: chlamydia, infection, bacteria, animal, pig, pathogenesis, symptoms, diagnostic methods.
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