深度学习辅助肾器官图像分析评估移植可行性

Ali Elmhamudi, Aliyu Abubakar, H. Ugail, Brian Thomson, C. Wilson, Mark Turner, D. Manas, S. Tingle, S. Colenutt, G. Sen, Jim Hunter, Meng Sun, Jackie Scully
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引用次数: 0

摘要

肾脏是人体的一个重要器官,它能排出体内的有毒废物,并维持水、矿物质和盐的平衡。近年来,这一重要器官的功能失调已成为一个重大的公共卫生问题。治疗急性肾衰竭最可行的方法是肾移植。健康的替代品需要来自健康的供体,经过经验丰富的临床医生的严格检查,以确定其活力。然而,整个过程耗时,不可靠,并且有很高的观察者内部和观察者之间的变化。基于这些原因,我们提出了一种基于机器学习的方法,使用照片样本来评估供体器官的健康状况。深度学习模型VGG-16和DenseNet121用于从标记为1、2、3、4和5的120个器官中提取特征,其中得分1和2为好,得分3为一般(不确定),得分4和5为差。随机森林回归器和支持向量回归器经过训练,然后用于预测外科医生得出的评分标签,确定器官是否可以移植或应该丢弃。结果表明,这种性质的算法在决定肾脏器官的可移植性方面有很长的路要走。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Deep Learning Assisted Kidney Organ Image Analysis for Assessing the Viability of Transplantation
The kidney is a vital organ in humans that removes toxic waste from the body and maintains the balance between water, minerals, and salts. Malfunctioning of this vital organ has become one of the significant public health concerns in recent years. The most viable way to treat patients with acute kidney failure is via transplantation. A healthy substitute is required from a healthy donor, which goes through rigorous examination by experienced clinicians to ascertain its vitality. However, the whole procedure is time-consuming, not reliable, and has high intra-observer and inter-observer variations. For these reasons, we proposed a machine learning-based approach using photographic samples to assess the health of the donor organ. Deep learning models, VGG-16 and DenseNet121, were used for feature extraction from 120 organs labelled 1,2,3,4 and 5, where scores 1 and 2 are good, score 3 is fair (uncertain), and 4 and 5 as poor. Random Forest Regressor and Support Vector Regressor were trained and then used to predict the surgeon-derived score labels, determining whether an organ is transplantable or should be discarded. The results indicate an algorithm of this nature could go a long way show in deciding the transplantability of a kidney organ.
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