[细胞抑制剂和右旋糖酐铁氧体联合应用于白血病P-388小鼠的抗肿瘤活性]。

Eksperimental'naia onkologiia Pub Date : 1990-01-01

N A Brusentsov, T Iu Glazkova, N P Iavorskaia, N Ia Iurchenko

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引用次数: 0

摘要

将阿霉素、放线菌素、玫瑰素、甲氨蝶呤、顺铂、肌酵素、红霉素、环磷酰胺、5-氟尿嘧啶或福托萘啶的水溶液与右旋糖酐铁氧体配伍。用100万小鼠P388白血病细胞接种BDF1小鼠24小时后，将所得组合物腹腔注射。这些药物与右旋糖酐铁氧体联合使用时，抗肿瘤活性完全保留。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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[Antineoplastic activity of combinations of cytostatics and dextran-ferrite administered to mice with leukemia P-388].

Water solutions of adriblastin, dactinomycin, rosevin, methotrexate, cisplatin, sarcolysine, rubomycin, cyclophosphamide, 5-fluorouracil or ftorafur were combined with dextran ferrite. The obtained compositions were injected i.p. to BDF1 mice 24 hours after they were inoculated with one million of murine P388 leukemic cells. Antitumor activity was fully retained for each of these agents in combination with dextran ferrite.

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Eksperimental'naia onkologiia

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