用于双聚类和聚类比较的自动基因本体软件工具

2009 IEEE Symposium on Computational Intelligence in Bioinformatics and Computational Biology Pub Date : 2009-03-30 DOI:10.1109/CIBCB.2009.4925723

Fadhl M. Al-Akwaa, Y. Kadah

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引用次数: 12

摘要

我们提出了一个自动基因本体(AGO)软件作为一个灵活的，开源的Matlab软件工具，允许用户轻松地比较双聚类和聚类方法的结果。该软件提供了几种方法来区分和比较候选算法的结果。结果表明，双聚类/聚类算法可以被视为集成模块，以恢复微阵列数据集中的有趣模式。AGO的进一步应用可以解决基因调控网络的降维问题。可用性:AGO和帮助文件可在http://home.k-space.org/FADL/Downloads/AGO_prgram.zip上获得

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An automatic gene ontology software tool for bicluster and cluster comparisons

We propose an Automatic Gene Ontology (AGO) software as a flexible, open-source Matlab software tool that allows the user to easily compare the results of the bicluster and cluster methods. This software provides several methods to differentiate and compare the results of candidate algorithms. The results reveal that bicluster/cluster algorithms could be considered as integrated modules to recover the interesting patterns in the microarray datasets. The further application of AGO could to solve the dimensionality reduction of the gene regulatory networks. Availability: AGO and help file is available at http://home.k-space.org/FADL/Downloads/AGO_prgram.zip

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2009 IEEE Symposium on Computational Intelligence in Bioinformatics and Computational Biology

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