Rare Side Effects After Inactiveted Sars-Cov-2 Vaccine (Coronavac)

Objective: To evaluate the frequency, type, onset time, and intensity of the side effects after the Coronavac vaccination in healthcare workers (HCW) and elderly people and also to determine whether COVID-19 disease occurs after vaccination in HCW. Methods: HCW and elderly people who were vaccinated in Gaziantep Medical Park were the cohorts of the study. A questionnaire was applied to HCW, and the data of elderly people were obtained from medical records. The questionnaire had demographic data, medical history also included COVID-19-related and side effects of the Coronavac vaccine. Results: Four hundred twenty-seven questionnaires were analyzed. The most common adverse reaction was pain at the injection site. The incidences of pain after the first and second injections were 23.8% (102/427) and 12.8% (52/405), respectively. And most common systemic side effect was fatigue with an incidence of 18.2% and 10.3% after each dose, respectively. Side effects that kept HCW from going to work after vaccination were not observed. After the two doses of vaccination, only 7 HCW had mild COVID-19 infection. One had a COVID-19 infection after 7 days of the first dose. 354 medical records of elderly people were evaluated. Only one of them reported urticaria after the first dose. Conclusions: Our study found that Coronavac is a well-tolerated and effective vaccine.