球形磷酸钙的合成及应用研究进展

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摘要

磷酸钙在药物输送、骨再生和组织工程等生物医学应用中的优势已得到认可。本文综述了球形磷酸钙的研究现状,包括球形颗粒、球形核和球形壳。采用仿生再矿化、海水法和水热法研究了先进的球粒制造和表征方法。本综述重点介绍了它们在牙科和疫苗应用中的应用。最后,简要总结了当前面临的挑战和未来的展望。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Recent advanced development of calcium phosphate in spherical form: syntheses and applications
The advantages of calcium phosphate in biomedical applications such as drug delivery, bone regeneration and tissue engineering have been recognized. An overview of calcium phosphate in spherical form including spherical particles, spherical core and spherical shell was carried out in this work. Advanced spheres manufacturing as well as characterisation methodologies by biomimic remineralisation, seawater and hydrothermal methods was investigated. Their use in dental and vaccine applications was focused and presented in this review. Finally, a brief conclusion of the existing challenges and future perspective are presented.
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