S-100蛋白免疫组化检测牙源性肿瘤和囊肿中的朗格汉斯细胞。

Basic and applied histochemistry Pub Date : 1990-01-01
N Murase, Y Tatemoto, Y Iwai, Y Okada, M Mori
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引用次数: 0

摘要

采用免疫组化方法,在牙源性上皮肿瘤(71例)、根状囊肿(40例)、滤泡囊肿(28例)、牙源性角化囊肿(11例)、原始囊肿(7例)和裂囊囊肿(6例)中证实朗格汉斯细胞(LCs)表达S-100蛋白。使用S-100蛋白多克隆抗血清,在肿瘤或囊性上皮中发现阳性lc,树突状或不规则形状,有时在基质结缔组织中发现。61例成釉细胞瘤中S-100染色阳性lccs的发生率为11例,40例根状囊肿中为22例,28例滤泡囊肿中为3例,牙源性肿瘤和囊性疾病的其他病变均缺乏lccs。S-100蛋白阳性的lc通常伴有高度的炎性浸润;相反,阴性病例也普遍缺乏炎症反应。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Langerhans cells in odontogenic tumours and cysts as detected by S-100 protein immunohistochemistry.

Immunohistochemical demonstration of S-100 protein in Langerhans cells (LCs) was made in odontogenic epithelial tumours (71 cases), radicular cysts (40 cases), follicular cysts (28 cases), odontogenic keratocysts (11 cases), primordial cysts (7 cases) and fissual cysts (6 cases). With the use of polyclonal antiserum against S-100 protein, positive LCs, dendrical or irregular in shape were found in tumour or cystic epithelia, and sometimes in stromal connective tissue. Incidence of positive S-100 staining LCs was 11 cases out of 61 ameloblastomas, 22 cases out of 40 radicular cysts, 3 cases of 28 follicular cysts, and other lesions in both odontogenic tumours and cystic diseases lacked LCs. The cases with S-100 protein positive LCs were usually accompanied with a high degree of inflammatory infiltration in their lesions; on the contrary, the negative cases also generally lacked inflammatory responses.

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