病人血液管理:麻醉师的观点

Taehee Kim, M. Jeong
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引用次数: 1

摘要

输血通常被认为是解决手术中贫血和失血的方法。输血是纠正贫血的一种非常高效和有效的方法,但越来越多的证据表明输血不能改善预后,而且发病率和死亡率呈剂量依赖性增加[1,2]。有研究表明,即使输入一个单位的填充红细胞(红细胞)也会增加30天死亡率、并发症死亡率、肺炎和败血症[3]。因此,最好避免不必要的输血或尽量减少输血。在外科患者中,患者血液管理的重点是贫血管理,尽量减少失血,适当输血以降低手术风险,改善术后患者预后。术前贫血的识别和管理是在手术前优化患者状态的一个机会,从而减少输血,并可能提高手术恢复和相关的术后结果。为了减少术中出血,需要采用复杂的方法,如麻醉策略和手术技术、药物干预和细胞抢救。本文从麻醉医师的角度对血液管理的研究进行综述。凝血功能障碍的治疗和血液成分治疗未包括在本综述中。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Patient Blood Management: Anesthesiologist's Perspectives
Blood transfusion is generally considered to be the solution of anemia and blood loss during surgery. Transfusion is a very efficient and effective method to correct anemia, but there has been increasing evidence that blood transfusion does not lead to improved outcomes and that morbidity and mortality increase in a dose-dependent manner [1,2]. It has been shown that even a single unit of transfused packed red blood cells (PRBCs) can increase 30day mortality, complicated mortality, pneumonia and sepsis [3]. Therefore, it is preferable to avoid unnecessary blood transfusion or to minimize blood transfusion. In surgical patients, patient blood management focuses on anemia management, minimization of blood loss, appropriate transfusion for reducing surgical risk, and improving patient outcome after surgery. Recognition and management of pre-operative anemia represent an opportunity to optimize patient status before surgery, thereby reducing blood transfusion and potentially improving recovery from surgery and associated postoperative outcomes. A complex approach such as anesthetic strategy and operative techniques, pharmacological intervention, and cell salvage is required to reduce bleeding during surgery. In this review, we reviewed the studies about blood management in the stance of anesthesiologists. Management of coagulopathy and blood component therapy was not included in this review.
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