药物释放分层分数模型的数值研究

Proceedings of 2010 IEEE/ASME International Conference on Mechatronic and Embedded Systems and Applications Pub Date : 2010-07-15 DOI:10.1109/MESA.2010.5551997

Xicheng Li, Wen Chen

{"title":"药物释放分层分数模型的数值研究","authors":"Xicheng Li, Wen Chen","doi":"10.1109/MESA.2010.5551997","DOIUrl":null,"url":null,"abstract":"A layered model describing the drug delivery from polymeric coating into arteries after stenting procedures is developed. By the aid of the numerical technique, the effects of the order of the fractional derivative and the permeability of the membrane are examined. The results show that the order of the fractional derivative and the permeability affect the diffusion process in different ways. It can be used to study the effect of different coating parameters and configurations on the drug release.","PeriodicalId":406358,"journal":{"name":"Proceedings of 2010 IEEE/ASME International Conference on Mechatronic and Embedded Systems and Applications","volume":"30 2","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2010-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Numerical study on a layered fractional model of drug release\",\"authors\":\"Xicheng Li, Wen Chen\",\"doi\":\"10.1109/MESA.2010.5551997\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"A layered model describing the drug delivery from polymeric coating into arteries after stenting procedures is developed. By the aid of the numerical technique, the effects of the order of the fractional derivative and the permeability of the membrane are examined. The results show that the order of the fractional derivative and the permeability affect the diffusion process in different ways. It can be used to study the effect of different coating parameters and configurations on the drug release.\",\"PeriodicalId\":406358,\"journal\":{\"name\":\"Proceedings of 2010 IEEE/ASME International Conference on Mechatronic and Embedded Systems and Applications\",\"volume\":\"30 2\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2010-07-15\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Proceedings of 2010 IEEE/ASME International Conference on Mechatronic and Embedded Systems and Applications\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1109/MESA.2010.5551997\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Proceedings of 2010 IEEE/ASME International Conference on Mechatronic and Embedded Systems and Applications","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1109/MESA.2010.5551997","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}

引用次数: 0

摘要

建立了一个描述药物在支架植入后从聚合物涂层进入动脉的分层模型。借助于数值方法，考察了分数阶导数阶数和膜渗透率的影响。结果表明，分数阶导数的阶数和渗透率对扩散过程有不同的影响。该方法可用于研究不同包膜参数和结构对药物释放的影响。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

Numerical study on a layered fractional model of drug release

A layered model describing the drug delivery from polymeric coating into arteries after stenting procedures is developed. By the aid of the numerical technique, the effects of the order of the fractional derivative and the permeability of the membrane are examined. The results show that the order of the fractional derivative and the permeability affect the diffusion process in different ways. It can be used to study the effect of different coating parameters and configurations on the drug release.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Proceedings of 2010 IEEE/ASME International Conference on Mechatronic and Embedded Systems and Applications

自引率

0.00%

发文量