镍/铜协同催化芳基酸酐与苯并恶唑的C-O / C-H偶联脱羰异芳基化

IF 3.6 2区化学 Q1 CHEMISTRY, ORGANIC

Journal of Organic Chemistry Pub Date : 2022-12-29 DOI:10.1021/acs.joc.2c01449

Cheng-Yi Wang, Rui Tian, Jia-Xin Li and Yong-Ming Zhu*,

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引用次数: 1

摘要

研究了镍/铜催化芳基酸酐C-O / C-H偶联脱羰杂芳化合成2-芳基苯并恶唑衍生物的新策略。该反应是由一种用户友好、价格低廉、空气和湿度稳定的Ni预催化剂促进的。该工艺已成功合成了多种2-芳基苯并恶唑衍生物，具有良好的官能团耐受性，产品收率中等至优异。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Nickel/Copper Cooperative Catalysis Decarbonylative Heteroarylation of Aryl Anhydrides with Benzoxazoles via C–O/C–H Coupling

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Nickel/Copper Cooperative Catalysis Decarbonylative Heteroarylation of Aryl Anhydrides with Benzoxazoles via C–O/C–H Coupling

A new strategy for the synthesis of 2-arylbenzoxazole derivatives via nickel-/copper-catalyzed decarbonylative heteroarylation of aryl anhydrides via C–O/C–H coupling has been developed. The reaction is promoted by a user-friendly, inexpensive, and air- and moisture-stable Ni precatalyst. A variety of 2-arylbenzoxazole derivatives have been successfully synthesized and have good functional group tolerance in this process, which afforded products in moderate-to-excellent yields.

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来源期刊

Journal of Organic Chemistry 化学-有机化学

CiteScore

6.20

自引率

11.10%

发文量

1467

审稿时长

2 months

期刊介绍： Journal of Organic Chemistry welcomes original contributions of fundamental research in all branches of the theory and practice of organic chemistry. In selecting manuscripts for publication, the editors place emphasis on the quality and novelty of the work, as well as the breadth of interest to the organic chemistry community.