Malignant Transformation of Labial Lichen Planus: A Rare Case Report

Introduction Oral Lichen Planus (OLP) is a T-cell-mediated chronic inflammatory disease of the oral mucosa. Its possible malignant potential remains a serious debate issue. The World Health Organization defined the pre-malignant condition as "a generalized condition associated with a significantly increased risk of cancer" and includes OLP in this classification [1]. The major topic of discussion is whether to consider OLP as an intrinsically premalignant condition or simply as a facilitator of the action of the carcinogenic agents Such as smoking, alcoholism, nutritional errors, poor hygiene, immunosuppression and oncogenic viruses.