{"title":"基于新距离和新分数函数的多序列比对算法","authors":"A. Mokaddem, M. Elloumi","doi":"10.1109/DEXA.2013.43","DOIUrl":null,"url":null,"abstract":"In this paper, we present our new progressive alignment algorithm, called Motalign, for Multiple Sequence Alignment (MSA). Our algorithm adopts a new profile based distance [1] to compare two biological sequences and a new score function, called gPSP, to align profiles. We benchmarked our algorithm on different benchmarks. We compared the results obtained by our algorithm to those obtained by other ones, like CLUSTALW2, MUSCLE and MAFFT, by using the Column Score (CS) [2] and the Sum of Pairs Score (SPS) [2]. We obtained interesting results.","PeriodicalId":428515,"journal":{"name":"2013 24th International Workshop on Database and Expert Systems Applications","volume":"15 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2013-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"7","resultStr":"{\"title\":\"Motalign: A Multiple Sequence Alignment Algorithm Based on a New Distance and a New Score Function\",\"authors\":\"A. Mokaddem, M. Elloumi\",\"doi\":\"10.1109/DEXA.2013.43\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"In this paper, we present our new progressive alignment algorithm, called Motalign, for Multiple Sequence Alignment (MSA). Our algorithm adopts a new profile based distance [1] to compare two biological sequences and a new score function, called gPSP, to align profiles. We benchmarked our algorithm on different benchmarks. We compared the results obtained by our algorithm to those obtained by other ones, like CLUSTALW2, MUSCLE and MAFFT, by using the Column Score (CS) [2] and the Sum of Pairs Score (SPS) [2]. We obtained interesting results.\",\"PeriodicalId\":428515,\"journal\":{\"name\":\"2013 24th International Workshop on Database and Expert Systems Applications\",\"volume\":\"15 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2013-08-26\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"7\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"2013 24th International Workshop on Database and Expert Systems Applications\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1109/DEXA.2013.43\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"2013 24th International Workshop on Database and Expert Systems Applications","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1109/DEXA.2013.43","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 7
摘要
本文提出了一种新的用于多序列比对(MSA)的渐进式比对算法——Motalign。我们的算法采用一种新的基于轮廓的距离[1]来比较两个生物序列，并采用一种新的评分函数gPSP来对齐轮廓。我们在不同的基准上对我们的算法进行了基准测试。我们使用Column Score (CS)[2]和Sum of Pairs Score (SPS)[2]将我们的算法得到的结果与CLUSTALW2、MUSCLE、MAFFT等算法得到的结果进行比较。我们得到了有趣的结果。
Motalign: A Multiple Sequence Alignment Algorithm Based on a New Distance and a New Score Function
In this paper, we present our new progressive alignment algorithm, called Motalign, for Multiple Sequence Alignment (MSA). Our algorithm adopts a new profile based distance [1] to compare two biological sequences and a new score function, called gPSP, to align profiles. We benchmarked our algorithm on different benchmarks. We compared the results obtained by our algorithm to those obtained by other ones, like CLUSTALW2, MUSCLE and MAFFT, by using the Column Score (CS) [2] and the Sum of Pairs Score (SPS) [2]. We obtained interesting results.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
