{"title":"国际标准化比例监测口服抗凝治疗的采用与验证:1989年的情况。","authors":"A M van den Besselaar","doi":"10.1007/BF02910151","DOIUrl":null,"url":null,"abstract":"<p><p>The INR/ISI system has been validated in multicenter trials. The system provides a reliable scale for the intensity of oral anticoagulation. It has been recognized that the ISI is slightly dependent on the instrument used for prothrombin time determination. External quality assessment (EQA) of the INR in national programs should be stimulated. EQA results suggest that the precision of the INR can be improved. Many physicians prescribing coumarin congeners are not familiar with the INR system. Improvement of the situation can only be achieved by continuous education.</p>","PeriodicalId":76092,"journal":{"name":"La Ricerca in clinica e in laboratorio","volume":"20 1","pages":"75-81"},"PeriodicalIF":0.0000,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/BF02910151","citationCount":"1","resultStr":"{\"title\":\"Adoption and validation of the international normalized ratio for monitoring oral anticoagulant therapy: the situation in 1989.\",\"authors\":\"A M van den Besselaar\",\"doi\":\"10.1007/BF02910151\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>The INR/ISI system has been validated in multicenter trials. The system provides a reliable scale for the intensity of oral anticoagulation. It has been recognized that the ISI is slightly dependent on the instrument used for prothrombin time determination. External quality assessment (EQA) of the INR in national programs should be stimulated. EQA results suggest that the precision of the INR can be improved. Many physicians prescribing coumarin congeners are not familiar with the INR system. Improvement of the situation can only be achieved by continuous education.</p>\",\"PeriodicalId\":76092,\"journal\":{\"name\":\"La Ricerca in clinica e in laboratorio\",\"volume\":\"20 1\",\"pages\":\"75-81\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1990-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1007/BF02910151\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"La Ricerca in clinica e in laboratorio\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1007/BF02910151\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"La Ricerca in clinica e in laboratorio","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1007/BF02910151","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Adoption and validation of the international normalized ratio for monitoring oral anticoagulant therapy: the situation in 1989.
The INR/ISI system has been validated in multicenter trials. The system provides a reliable scale for the intensity of oral anticoagulation. It has been recognized that the ISI is slightly dependent on the instrument used for prothrombin time determination. External quality assessment (EQA) of the INR in national programs should be stimulated. EQA results suggest that the precision of the INR can be improved. Many physicians prescribing coumarin congeners are not familiar with the INR system. Improvement of the situation can only be achieved by continuous education.