心肺指数随进行性负荷变化的生理研究

S. Kupriyanov, S. V. Bochkarev, L. M. Semenova, N. Y. Kruglikov, I. Myasnikova, D. I. Nizova, N. Zhuravleva, Alhasan Mohammad
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摘要

目标。本研究的主要目的是建立一个心肺系统状态系数,该系数将考虑到外呼吸和血流动力学活动的频率和功率特性。将该系数的信息量与普遍接受的希尔德布兰特系数进行比较。材料和方法:对154名看起来健康的男女青年进行了检查。在每分钟40次蹬车节奏的自行车计力器上,提供了五个标准阶段的短期体育锻炼负荷,范围从可忽略到适度。负荷前、负荷高峰和负荷后分别进行肺活量、血压计和脉搏测量。同时记录每位受试者指定的参数。收缩容积采用Starr公式计算,随后定义心分钟输出量。使用Statistica®7.0软件包(StatSoft Inc., USA)进行统计分析。评估结果的显著性采用学生t检验和符号检验。结果。在低短期体育锻炼的情况下,肺通气量的增加是由于外部呼吸振幅的更大反应性,而呼吸运动频率的变化在较小程度上是由于呼吸运动频率的变化。这类呼吸成分的反应在心肺相互作用中效率更高。在给定条件下,呼吸成分的主导地位保证了机体的适应性,而全身动脉压和脉搏的反应则变得不那么明显、不那么稳定。考虑到呼吸和心血管活动的功率特性变化具有更大的适应性重要性,提出了一个心肺系统状态系数- MBV/RMV(分钟血流量与呼吸分钟容量之比)。给定的因子被证明具有显著更大的信息价值和对一般公认的希尔德布兰特系数的敏感性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
PHYSIOLOGICAL STUDIES ON THE CARDIOPULMONARY INDEX CHANGES IN ADAPTATION TO PROGRESSIVE PHYSICAL LOADS
Objective. The main purpose of the research was to develop a coefficient of cardiorespiratory system status, which will take into account both frequency and power characteristics of external respiration and hemodynamics activity. Compare an informativeness of this coefficient with a universally accepted Hildebrandt one. Materials and Methods. 154 apparently healthy young people of both sexes were examined. On a bicycle ergometer with a pedaling rhythm of 40 per minute, five standard stages of short-term physical exercise load ranging from negligible to moderate were provided. Spirography, tonometry and pulsometry were carried out before loading, at its peak and after it. The parameters specified were recorded for each subject simultaneously. Systolic volume was calculated using Starr formula with subsequent defining cardiac minute output. Statistical analysis was performed using Statistica ® 7.0 package (StatSoft Inc., USA). Assessment of results’ significance was calculated using Student's t-test and sign test. Results. In the case of low short-term physical exercises pulmonary ventilation is increased due to greater reactivity of external breathing amplitude and to a lesser extent due to change in the frequency of respiratory movements. This type of reactions of the respiratory component in cardiorespiratory interaction is more efficient. In the given conditions, body’s adaptation is ensured by breathing component dominance, while responses of systemic arterial pressure and pulse turn out to be less pronounced, less stabile. Taking into account greater adaptive importance in power characteristics changes of respiratory and cardiovascular activity, a coefficient of cardiorespiratory system status is proposed – MBV/RMV (ratio of minute blood flow volume to respiratory minute volume). The given factor is demonstrated to have significantly greater informative value and sensitivity to generally recognized Hildebrandt coefficient.
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