使用低强度激光作为放射增敏剂的恶性肿瘤放疗

P. Polyakov, O. Bychenkov, N. Larionova, D. Rogatkin
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引用次数: 0

摘要

提出了一种利用低强度激光(LILR)进行放射增敏的新方法。讨论了所涉及的理论和方法方面以及专门研制的仪器。78例II-IV型皮肤和口咽肿瘤患者批准了放疗联合LILR。联合LILR作为放射线致敏程序及后续放疗并未增加放射线局部反应的程度,治疗结果得到可靠改善:由于放射线致敏,显著+显著肿瘤消退的总指数可信度从65.7 +/- 5.8%上升至84.3 +/- 4.3% (t = 2.58;P < 0.05),三年生存指数从44.6 +/- 5.5%上升到60.3 +/- 5.5% (t = 2.02;P < 0.05)。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Radiotherapy of malignant tumors using low-intensity laser radiation as a radiosensitizer
A new method of radiosensitization is offered using low- intensity laser radiation (LILR). Theoretic and methodological aspects involved as well as specially developed apparatus are discussed. Radiotherapy combined with LILR was approved in 78 patients with cutaneous and oropharyngeal tumors II-IV. Combined treatment with LILR as a radiosensitizing procedure and subsequent radiotherapy doesn't increase the degree of local reactions in response to radiation, and provide the reliable improvement of the therapy outcome: the total index of significant plus pronounced tumor regression, owing to the radiosensitization, trustworthy rises from 65.7 +/- 5.8% to 84.3 +/- 4.3% (t equals 2.58; p < 0.05), the three-year survival index--from 44.6 +/- 5.5% up to 60.3 +/- 5.5% (t equals 2.02; p < 0.05).
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