浅表皮肤真菌病:一项前瞻性临床真菌学研究

A. Surekha, G. Rameshkumar, K. Sridevi, Murthy Ds, G. Usha, G. Bharathi
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引用次数: 10

摘要

背景:由于有利的气候条件,贫穷,卫生条件差和过度拥挤,皮肤霉菌病在印度更为普遍。关于印度浅表性皮肤真菌病的已发表数据很少。方法:对198例浅表性皮肤真菌病患者的人口学特征、临床谱及发展危险因素进行前瞻性研究。结果:患者平均年龄34.1±15.3岁;男性108例(54.5%)。大多数患者(50.5%)属于中低社会经济地位(修正库普斯瓦米分类IV类)。大多数患者(69.7%)表现为皮肤真菌病。在浅表性皮肤真菌病中,体癣是最常见的临床类型(29.3%)。氢氧化钾mount阳性占77.7%,培养阳性占30.8%。红毛霉(Trichophyton rubrum)是最常见的分离种(64%)。使用logistic回归的多变量分析显示,年龄较大(> 50岁)是体癣发展的独立预测因子(p<0.001)。结论:我们的观察结果表明,浅表皮肤真菌病是发病的重要原因,应仔细寻找,特别是老年人,以便制定有效的治疗措施。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Superficial dermatomycoses: a prospective clinico-mycological study
Background: Dermatomycoses are more prevalent in India due to favourable climatic conditions, poverty, poor hygiene and overcrowding. Sparse published data are available regarding superficial dermatomycoses from India. Methods: In this prospective study, demographic characteristics, clinical spectrum and risk factors for the development were studied in 198 patients with superficial dermatomycoses. Results: Their mean age was 34.1 ± 15.3 years; there were 108 (54.5%) males. Majority of the patients (50.5%) belonged to upper-lower socio-economic status (Class IV as per modified Kuppuswamy’s classification). Most of the patients (69.7%) had presented with dermatophytoses. Among superficial dermatomycoses, tinea corporis was the most common (29.3%) clinical type. Potassium hydroxide mount was positive in 77.7% and culture was positive in 30.8%. Trichophyton rubrum was the most common species isolated (64%). Multivariable analysis using logistic regression revealed older age (> 50 years) to be an independent predictor for the development of tinea corporis (p<0.001). Conclusions: Our observations suggest that superficial dermatomycoses are an important cause of morbidity and should be carefully searched for especially in the elderly so that effective curative treatment can be instituted.
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