马卓林溃疡:布拉柴维尔7(07)例报告

J. N. Malanda, Sophie Bayonne Kombo, Grâce Dulcinée Mabiala Maye, Augustin Bambara Tozoula, Aubièrge Victoire Kimpamboudi Matondo, E. Ndounga, Jean Bernard Nkoua Mbon
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摘要

马卓林溃疡(Marjolin's Ulcer, MU)是指发生在旧的不稳定疤痕上的所有皮肤恶性肿瘤。本研究的总体目的是报告刚果的MU病例并进行文献回顾。这是1998年1月至2017年12月在布拉柴维尔大学教学医院进行的一项回顾性研究(为期20年)。组织学证实为皮肤癌的住院患者,发生在瘢痕性皮肤病变进展。收集流行病学、临床、组织病理学和治疗变量。确定了7例患者。他们占皮肤癌的1.9%。中年为44.4岁。女性占主导地位,性别比例为2.5。所有患者(100%)的病因均为烧伤瘢痕。所有患者均未得到适当的初始伤口护理。MU发病的平均时限为34年。解剖病理检查显示所有患者(100%)为鳞状细胞癌。1例(01例)患者(14.28%)行癌变检查。其中截肢3例(03例),占42.85%;骨折2例(02例),占28.57%。化疗6例(06例),占85.71%。5例(05)例(71.42%)患者死亡,1例女性患者完全缓解(14.28%)。本研究证实了MU的稀缺性和严重性;它也揭示了高死亡率的诊断迟发性。提高烧伤和慢性损伤的护理质量,提高患者的护理意识,并对护理人员进行培训,有助于改善烧伤和慢性损伤的预后。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Marjolin's Ulcer: Seven (07) Cases Studied in Brazzaville
Introduction Marjolin's Ulcer (MU) means all cutaneous malignancies developed on old unsteady scars. The general objective of this study was to report the MU cases in Congo with a literature review. It was a retrospective study conducted at University Teaching Hospital in Brazzaville from January 1998 to December 2017 (a 20-year period). The in-patients for cutaneous cancer histologically confirmed, arose on scarring skin lesions progressive were included. The epidemiological, clinical, histopathological and therapeutical variables were collected. Seven patients were identified. They represented 1.9% of skin cancers. The middle age was 44.4 years. The female predomination was noted with a sex ratio of 2.5. The burn scars was the etiological factor found to all our patients (100%). None of patients had an appropriate care of initial wound. The average time limit of the onset of MU was 34 years. The anatomopathologic examination revealed a squamous cell carcinoma to all our patients (100%). Carcinologic exeresis carried out to one (01) patient (14.28%). The amputation: three (03) patients (42.85%) and the disarticulation: two (02) patients (28.57%). The chemotherapy six (06) patients (85.71%). The decease arose five (05) patients (71.42%) and the entire remission reached to a woman patient (14.28%). This study confirmed the rareness and the severity MU; it also reveals the diagnosis lateness of a great death-rate. The care of quality of burns and chronic injuries, the awareness of patients together with the care givers training could help to improve the prognosis of this affection.
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