Long-term transformative effects and integration challenges of psychedelic experiences

This study looked into the transformative effects and integration challenges of psychedelic experiences with psilocybin and lysergic acid diethylamide (LSD) for the Romanian population. The aim was to determine the long-term transformative effects and challenges individuals might encounter during the integration process. The study employed a sequential mixed method design, using qualitative interpretative phenomenological analysis (IPA) with six interview participants, followed by a quantitative survey with 39 responses. The qualitative data analysis led to a multi-layered hierarchical model of themes and subordinate themes ranging from changes in perception of self, emotional transformation, spiritual transformation, interpersonal transformation, to personal, interpersonal, and cultural integration challenges. The survey results made it possible to compare the interview group with a broader national sample, and the sample's statistical similarity provided extra validity to the smaller sample of qualitative thematic findings. The psychedelic experiences inspired long-term transformation and persisting positive effects in all participants. However, the nature and challenges of the integration journey ranged from mild difficulties to more substantial ones. Interpersonal and cultural challenges such as communication challenges, absence of a supportive community and oppressive legislation were common. Further in-depth cross-cultural studies on the topic are necessary to confirm cultural differences.